Buspirone: Pharmacokinetics,side effects and mechanism of action
Buspirone, also known as Buspa, and Hisblon, is a new generation of non-BZ anxiolytic drug with anti-anxiety effects and a different mechanism of action from that of benzodiazepines.
Oct 12，2019 Chemical pesticides 
Toxicity and Uses of Iprobenfos
Iprobenfos is a systemic organophosphorus fungicide, and mainly used in the control of rice blast with a stronger efficacy and longer duration than that of Kitazin.
Oct 12，2019 Chemical pesticides Biological activity of Inhibitor AC220
Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively.
Oct 11，2019 InhibitorsBiological activity of PLX-4720
PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations).
Oct 11，2019 InhibitorsCP-690550 as an Inhibitor
Tofacitinib citrate is a king of drugs developed by the US pharmaceutical company Pfizer for treating rheumatoid arthritis, trade name Xeljanz.
Oct 11，2019 InhibitorsBiological activity of GSK1120212
Trametinib (GSK1120212) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2.
Oct 11，2019 InhibitorsBiological activity ABT-888
Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays.
Oct 11，2019 Inhibitors
Preparation Method of Chlorine dioxide
Chlorine dioxide is a yellowish-green, irritating, neutral chlorine compound with the formula ClO2. It is liquefied into reddish brown liquid at 11℃, but solidified into orange red crystal at -59℃.
Oct 11，2019 Inorganic chemistry
Preparation Method of 5-Amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole
5-Amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole is an important intermediate used in the process for preparation of Fipronil.
Oct 11，2019 Pharmaceutical intermediates
Application and side effects of Allopurinol
Allopurinol is a xanthine oxidase inhibitor that reduces the production of uric acid. Allopurinol is used to prevent gout attacks by reducing uric acid production; high levels of uric acid may cause g
Oct 11，2019 API