MK-4827 (tosylate)
To validate that MK-4827 (Niraparib) inhibits PARP in these cell lines, A549 and H1299 cells are treated with 1 μM MK-4827 for various times and measured PARP enzymatic activity using a chemiluminesce
Aug 26，2019 Organic reagentsSynthesis of Ethyl Levulinate
In this study, 40 % H3PW12O40/ZrO2 catalyst was synthesized, characterized and tested for conversion of levulinic acid (LA) and ethanol (EtOH) to ethyl levulinate (EL). The catalyst was prepared throu
Aug 26，2019 Flavors and fragrances
The correlational research of Argireline
Most of us know that Argireline prevents the formation of expression wrinkles by somehow inhibiting muscle movement. For this reason, it is sometimes called Botox in a jar. But, in fact, they work ver
Aug 26，2019 Biochemical Engineering
Introduction of Ortho-phthalaldehyde
Based on this, a modified o-phthalaldehyde fluorometric analytical method has been established to determine ultratrace ammonium in natural waters. Experimental parameters, including reagent concentra
Aug 26，2019 Chemical Reagents
The application and pharmacologic action of Ibudilast
Ibudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain vo
Aug 23，2019 API
The pharmacologic action of Ulipristal Acetate
Ulipristal acetate is a selective progesterone receptor modulator.5 It is a partial agonist, exerting agonist and antagonist activity at the progesterone receptor. While it has been used in the medica
Aug 23，2019 APIUses for Resorcinol
Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorder
Aug 23，2019 Organic reagents
Dimefluthrin: A new pyrethroid insecticide agent
A series of 4-substituted-2,3,5,6-tetrafluorolbenzyl (1R,3R)-chrysanthemates were synthesized and evaluated for their insecticidal activity against Culex pipiens pallens (Coquillett). Among them, the
Aug 23，2019 Chemical pesticides 
The pharmacologic action of Silibinin
Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk t
Aug 22，2019 Biochemical Engineering
The uses and Pharmacologic action of Paclitaxel
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from
Aug 22，2019 API