ChemicalBook--->CAS DataBase List--->100665-42-7

100665-42-7

100665-42-7 Structure

100665-42-7 Structure
IdentificationBack Directory
[Name]

(20E)-3β,7β,15α-Trihydroxy-11,23-dioxo-5α-lanosta-8,20(22)-dien-26-oic acid
[CAS]

100665-42-7
[Synonyms]

Ganoderenic acid c
(20E)-3β,7β,15α-Trihydroxy-11,23-dioxo-5α-lanosta-8,20(22)-dien-26-oic acid
Lanosta-8,20(22)-dien-26-oicacid, 3,7,15-trihydroxy-11,23-dioxo-, (3b,7b,15a,20E)-
Lanosta-8,20(22)-dien-26-oic acid, 3,7,15-trihydroxy-11,23-dioxo-, (3β,7β,15α,20E)-
(3beta,7beta,15alpha,20E)-3,7,15-Trihydroxy-11,23-dioxo-lanosta-8,20(22)-dien-26-oic acid
[Molecular Formula]

C30H44O7
[MDL Number]

MFCD32197328
[MOL File]

100665-42-7.mol
[Molecular Weight]

516.67
Chemical PropertiesBack Directory
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[InChIKey]

DIEUZIPSDUGWLD-QYHYFQJXNA-N
[SMILES]

[C@@H]1(O)C(C2[C@](C)(CC1)C1=C([C@]3([C@@](CC1=O)(C)[C@@H](/C(/C)=C/C(=O)CC(C)C(O)=O)C[C@@H]3O)C)[C@@H](O)C2)(C)C |&1:0,4,10,11,16,29,32,r|
Hazard InformationBack Directory
[Description]

Ganoderenic acid C is a triterpene that has been found in G. lucidum. It is cytotoxic to H460 cancer cells (IC50 = 93 μM).
[Uses]

Ganoderenic acid C (GDC) is a triterpenoid extracted from Ganoderma lucidum (GL). GDC can be used to establish HPLC-DAD fingerprints of GL for quality control of GL products. Studies have shown that GDC has anticancer and anti-inflammatory effects. GDC binds to enzymes involved in the synthesis of DNA, RNA and proteins and can inhibit the activity of cancer cells. GDC also inhibits the production of prostaglandins, which leads to an anti-inflammatory effect.
[Definition]

ChEBI: Ganoderenic acid C is a triterpenoid.
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