| Identification | More | [Name]
(R)-4-Benzyl-2-oxazolidinone | [CAS]
102029-44-7 | [Synonyms]
2-OXAZOLIDINONE, 4-PHENYL-, (4R)-
2-OXAZOLIDINONE, 4-(PHENYLMETHYL)-, (4R)-
(4R)-4-BENZYL-1,3-OXAZOLIDIN-2-ONE
(4R)-4-BENZYLOXAZOLIDIN-2-ONE
(4R)-4-PHENYL-1,3-OXAZOLIDIN-2-ONE
(4R)-4-PHENYLOXAZOLIDIN-2-ONE
4-R-BENZYL-2-OXAZOLIDINONE
(4R)-PHENYL-2-OXAZOLIDINONE
(R)-(+)-4-BENZYL-2-OXAZOLIDINONE
(R)-4-BENZYL-2-OXAZOLIDINONE
(R)-(+)-4-BENZYL-2-OXAZOLIDONE
(R)-4-BENZYL-OXAZOLIDIN-2-ONE
(R)-(-)-4-PHENYL-2-OXAZOLIDINONE
(R)-(+)-4-PHENYL-2-OXAZOLIDINONE
(R)-4-PHENYL-2-OXAZOLIDINONE
(R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE
RBOX
(R)-PH-OXAZOLIDINONE
(R)-4-Benzyl-2-0xazolidinone
4-benzyl-2-0xazolidinone | [EINECS(EC#)]
600-264-2 | [Molecular Formula]
C9H9NO2 | [MDL Number]
MFCD00192393 | [Molecular Weight]
163.17 | [MOL File]
102029-44-7.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
88-90 °C | [alpha ]
62 º (C=1, CHCl3) | [Boiling point ]
309.12°C (rough estimate) | [density ]
1.1607 (rough estimate) | [refractive index ]
14.5 ° (C=5, MeOH) | [storage temp. ]
0-6°C | [solubility ]
Chloroform (Slightly) | [form ]
Crystalline Powder | [pka]
12.78±0.40(Predicted) | [color ]
White to almost white | [Optical Rotation]
[α]18/D +64°, c = 1 in chloroform | [Water Solubility ]
Insoluble in water. Soluble in Chloroform. | [Sensitive ]
Hygroscopic | [Usage]
An oxazolidinone used in chiral auxiliary asymetric synthesis | [BRN ]
4782551 | [InChI]
1S/C10H11NO2/c12-10-11-9(7-13-10)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,11,12)/t9-/m1/s1 | [InChIKey]
OJOFMLDBXPDXLQ-SECBINFHSA-N | [SMILES]
O=C1N[C@@H](CO1)Cc2ccccc2 | [CAS DataBase Reference]
102029-44-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H320 | [Precautionary statements ]
P264-P305+P351+P338+P337+P313 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
3-10 | [HS Code ]
29349900 | [Storage Class]
11 - Combustible Solids |
| Questions and Answers (Q&A) | Back Directory | [Description]
(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It
can be used in the preparation of enantiopure carbocyclic
nucleosides, which act as a HIV protease inhibitor. It can also be
used as a chiral auxiliary in the enantioselective synthesis of (2R,
2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids.
Its end product includes asymmetric single isomeric drugs such as
antitumor, anesthetic and entipasmodic products. | [References]
http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US
https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.
|
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
An oxazolidinone used in chiral auxiliary asymetric synthesis | [Uses]
intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan |
|
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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400-0056266 |
| Website: |
www.energy-chemical.com |
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