| Identification | More | [Name]
2-Oxazolidone | [CAS]
497-25-6 | [Synonyms]
2-OX
2-OXAZOLIDINONE
2-OXAZOLIDONE
oxazolidin-2-one
(2-hydroxyethyl)-carbamicacigamma-lactone
1,3-Oxazolidin-2-one
2-Oxazolidine
Carbamic acid, (2-hydroxyethyl)-, gamma-lactone
Oxazolidine
Oxazolidone
2-Oxazolidinone,99%
2-OXAZOLIDIONE
(2-hydroxyethyl)-carbamic acid gamma-lactone
2-OXAZOLIDINONE 98%
2-Oxotetrahydro-1,3-oxazole
2-Oxazolinone | [EINECS(EC#)]
207-840-9 | [Molecular Formula]
C3H5NO2 | [MDL Number]
MFCD00005268 | [Molecular Weight]
87.08 | [MOL File]
497-25-6.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white to yellow-beige crystals or powder | [Melting point ]
83-87 °C(lit.)
| [Boiling point ]
220 °C48 mm Hg(lit.)
| [density ]
1.2736 (rough estimate) | [refractive index ]
1.4940 (estimate) | [Fp ]
220°C/48mm | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly, Heated), Methanol (Slightly) | [form ]
Crystals or Powder | [pka]
12.78±0.20(Predicted) | [color ]
Off-white to yellow-beige | [Water Solubility ]
Soluble in water. | [BRN ]
106251 | [InChI]
1S/C3H5NO2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5) | [InChIKey]
IZXIZTKNFFYFOF-UHFFFAOYSA-N | [SMILES]
O=C1NCCO1 | [CAS DataBase Reference]
497-25-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Oxazolidin-2-one(497-25-6) | [EPA Substance Registry System]
497-25-6(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H317-H319-H315-H335 | [Precautionary statements ]
P280-P305+P351+P338-P261-P280a-P304+P340-P405-P501a | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36:Irritating to the eyes.
R43:May cause sensitization by skin contact.
R40:Limited evidence of a carcinogenic effect.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S37:Wear suitable gloves .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
RQ2450000
| [TSCA ]
Yes | [HS Code ]
29322980 | [Storage Class]
13 - Non Combustible Solids | [Toxicity]
TDLo orl-mus: 1000 mg/kg:ETA BCPCA62,168,59 |
| Hazard Information | Back Directory | [Chemical Properties]
off-white to yellow-beige crystals or powder | [Uses]
As an oxazole derivative used as an antibiotic, 2-Oxazolidone is also used in the preparation of compounds with antitumor activity and as a metabolite of Furazolidone (F864100).
| [Definition]
ChEBI: An oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2. | [Safety Profile]
Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx. | [Synthesis]
2-Oxazolidinone is synthesized by the following methods: 1) electrolytic cyclization and oxidation of hydroxyethyl formamide; 2) reaction of aminoethanol with CO2 gas; 3) reaction of epoxide with cyanuric acid or urea; 4) reaction of acrolein with isocyan | [Purification Methods]
Crystallise it from *benzene, dichloroethane, CHCl3 or EtOH. It is a cyclic urethane, and as such it is not very stable. [Katritzky et al. J Chem Soc Perkin II 145 1990, Beilstein 27 H 135, 27 II 259, 27 III/IV 2516.] |
|
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J & K SCIENTIFIC LTD.
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https://www.jkchemical.com |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
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Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956 |
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