Identification | Back Directory | [Name]
(R)-Amlodipine | [CAS]
103129-81-3 | [Synonyms]
d-Amlodipine (R)-Amlodipine (R)-(+)-Amlodipine Amlodipine (R)-Isomer (R)-Amlodipine USP/EP/BP d-Amlodipine,(R)-(+)-Amlodipine Amlodipine Impurity 15(R-Isomer) 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydro-3,5-Pyridinedicarboxylate (R)-3-ethyl-5-metyl-2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyrdine-3,5-dicarboxylate (R)-3-ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate (4R)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl)-6-methyl-1,4-dihydropyridine 3-O-ethyl 5-O-methyl (4R)-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate (4R)-2-[(2-AMinoethoxy)Methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-Methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (R)- 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4R)- | [Molecular Formula]
C20H25ClN2O5 | [MOL File]
103129-81-3.mol | [Molecular Weight]
408.88 |
Chemical Properties | Back Directory | [Melting point ]
101-103°C | [Boiling point ]
527.2±50.0 °C(Predicted) | [density ]
1.227±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
8.97±0.10(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/t17-/m1/s1 | [InChIKey]
HTIQEAQVCYTUBX-QGZVFWFLSA-N | [SMILES]
C1(COCCN)NC(C)=C(C(OC)=O)[C@@H](C2=CC=CC=C2Cl)C=1C(OCC)=O |
Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
(R)-Enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer. | [Uses]
(R)-Enantiomer of Amlodipine. A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer. | [Definition]
ChEBI: (R)-amlodipine is the (4R)-enantiomer of amlodipine. It is an enantiomer of a (S)-amlodipine. |
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