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113994-41-5

113994-41-5 Structure

113994-41-5 Structure
IdentificationBack Directory
[Name]

Dehydro Amlodipine (Amlodipine Impurity D)
[CAS]

113994-41-5
[Synonyms]

UK 55-410
Dehydro Amlodipine
Amlodipine Impurity D
AMlodipine EP IMpurity D
Amlodipine EP Impurity 1
Amlodipine EP Impurity D1
Dehydro Amlodipine Oxalate
AMlodipine USP Related CoMpound A
Amlodipine Besylate EP Impurity D
Amlodipine EP impurity D (USP R C A)
Dehydro Amlodipine (Amlodipine Impurity D)
3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxyla
3-Ethyl 5-Methyl Ester 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate
3-Ethyl, 5-methyl [2-(2-aminoethoxymethyl)-4-(2-chloroenyl) -6-methyl-3,5-pyridinedicarboxylate]fumarate
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
3-Ethyl, 5-Methyl [2-(2-aMinoethoxyMethyl)-4-(2-chlorophenyl)-6-Methyl-3,5-pyridinedicarboxylate] fuMarate
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester Oxalate
Amlodipine Related Compound A (15 mg) (3-Ethyl, 5-methyl [2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylate] fumarate)
[Molecular Formula]

C20H23ClN2O5
[MDL Number]

MFCD19705165
[MOL File]

113994-41-5.mol
[Molecular Weight]

406.86
Chemical PropertiesBack Directory
[Appearance]

White to Off-White Solid
[Melting point ]

106-108°C
[Boiling point ]

517.9±50.0 °C(Predicted)
[density ]

1.241±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Oil
[pka]

8.42±0.10(Predicted)
[color ]

Colourless to Pale Yellow
[Stability:]

Hygroscopic
[InChI]

InChI=1S/C20H23ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8H,4,9-11,22H2,1-3H3
[InChIKey]

APZSGEHAFPIYQZ-UHFFFAOYSA-N
[SMILES]

C1(COCCN)=NC(C)=C(C(OC)=O)C(C2=CC=CC=C2Cl)=C1C(OCC)=O
[CAS DataBase Reference]

113994-41-5
Hazard InformationBack Directory
[Chemical Properties]

White to Off-White Solid
[Uses]

Amlodipine impurity D
[Uses]

Dehydro Amlodipine is an Amlodipine (A633495) impurity.
[Synthesis]

Amlodipine EP impurity D can be prepared from amlodipine by dehydroxylation in the presence of a suitable oxidizing agent.

Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H335-H315
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Chlorobenzene-->Pyridine
[Preparation Products]

Amlodipine
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