| Identification | Back Directory | [Name]
Dehydro Amlodipine (Amlodipine Impurity D) | [CAS]
113994-41-5 | [Synonyms]
UK 55-410
Dehydro Amlodipine
Amlodipine Impurity D
AMlodipine EP IMpurity D
Amlodipine EP Impurity 1
Amlodipine EP Impurity D1
Dehydro Amlodipine Oxalate
AMlodipine USP Related CoMpound A
Amlodipine Besylate EP Impurity D
Amlodipine EP impurity D (USP R C A)
Dehydro Amlodipine (Amlodipine Impurity D)
3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxyla
3-Ethyl 5-Methyl Ester 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate
3-Ethyl, 5-methyl [2-(2-aminoethoxymethyl)-4-(2-chloroenyl) -6-methyl-3,5-pyridinedicarboxylate]fumarate
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
3-Ethyl, 5-Methyl [2-(2-aMinoethoxyMethyl)-4-(2-chlorophenyl)-6-Methyl-3,5-pyridinedicarboxylate] fuMarate
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester Oxalate
Amlodipine Related Compound A (15 mg) (3-Ethyl, 5-methyl [2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylate] fumarate) | [Molecular Formula]
C20H23ClN2O5 | [MDL Number]
MFCD19705165 | [MOL File]
113994-41-5.mol | [Molecular Weight]
406.86 |
| Chemical Properties | Back Directory | [Appearance]
White to Off-White Solid | [Melting point ]
106-108°C | [Boiling point ]
517.9±50.0 °C(Predicted) | [density ]
1.241±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Oil | [pka]
8.42±0.10(Predicted) | [color ]
Colourless to Pale Yellow | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C20H23ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8H,4,9-11,22H2,1-3H3 | [InChIKey]
APZSGEHAFPIYQZ-UHFFFAOYSA-N | [SMILES]
C1(COCCN)=NC(C)=C(C(OC)=O)C(C2=CC=CC=C2Cl)=C1C(OCC)=O | [CAS DataBase Reference]
113994-41-5 |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
Amlodipine impurity D | [Uses]
Dehydro Amlodipine is an Amlodipine (A633495) impurity. | [Synthesis]
Amlodipine EP impurity D can be prepared from amlodipine by dehydroxylation in the presence of a suitable oxidizing agent.
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