ChemicalBook--->CAS DataBase List--->10328-92-4

10328-92-4

10328-92-4 Structure

10328-92-4 Structure
IdentificationMore
[Name]

N-METHYLISATOIC ANHYDRIDE
[CAS]

10328-92-4
[Synonyms]

AKOS 226
MIA
N-METHYLISATOIC ANHYDRIDE
TIMTEC-BB SBB000196
1-Methyl-2H-3,1-benzoxazine-2,4(1H)-dione
2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl-
4(1h)-dione,1-methyl-2h-1-benzoxazine-2
N-Methyl ia
n-methylia
N-Methyl-N-carboxyanthranilic anhydride
N-METHYLISATOIC ANHYDRIDE, TECH., 90%
N-Methylisatoicanhydride,tech.,90%
1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione
1-Methyl-1,2-dihydro-4H-3,1-benzoxazine-2,4-dione
1-Methyl-1H-3,1-benzoxazine-2,4-dione
1-Methyl-4H-3,1-benzoxazine-2(1H),4-dione
[EINECS(EC#)]

233-714-8
[Molecular Formula]

C9H7NO3
[MDL Number]

MFCD00006815
[Molecular Weight]

177.16
[MOL File]

10328-92-4.mol
Chemical PropertiesBack Directory
[Appearance]

brownish chunks
[Melting point ]

165 °C (dec.)(lit.)
[Boiling point ]

309.06°C (rough estimate)
[density ]

1.3312 (rough estimate)
[vapor density ]

6.1 (vs air)
[refractive index ]

1.5200 (estimate)
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

Soluble in DMSO
[pka]

-2.24±0.20(Predicted)
[Sensitive ]

Moisture Sensitive
[CAS DataBase Reference]

10328-92-4(CAS DataBase Reference)
[EPA Substance Registry System]

2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- (10328-92-4)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
[WGK Germany ]

3
[RTECS ]

DM3140000
[TSCA ]

Yes
[HS Code ]

2934.99.4400
Hazard InformationBack Directory
[Chemical Properties]

brownish chunks
[Uses]

N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs, and is widely used for resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology.
[Application]

N-Methylisatoic anhydride was first condensed with ethanolamine to give N-(2-hydroxyethyl)-2-methylaminobenzamide. Cyclization of the latter with ethyl pyruvate gave quinazoline derivatives which, upon hydrolysis and dehydrative cyclization with l-methyl-2-chloropyridinium iodide, afforded the l,4-oxazines[3,4-]quinazoline.
[Definition]

ChEBI: A 3,1-benzoxazin-1,4-dione having an N-methyl substituent.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

N-METHYLISATOIC ANHYDRIDE(10328-92-4)MS
N-METHYLISATOIC ANHYDRIDE(10328-92-4)IR1
N-METHYLISATOIC ANHYDRIDE(10328-92-4)IR2
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

N-Methylisatoic anhydride, tech. 90%(10328-92-4)
[Sigma Aldrich]

10328-92-4(sigmaaldrich)
[TCI AMERICA]

N-Methylisatoic Anhydride,>95.0%(N)(10328-92-4)
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