| Identification | More | [Name]
3,5-Diiodo-L-thyronine | [CAS]
1041-01-6 | [Synonyms]
3,5-DIIODO-4-(4-HYDROXYPHENOXY)-L-PHENYLALANINE
3,5-DIIODO-L-THYRONINE
L-TYROSINE, O-(4-HYDROXYPHENYL)-3,5-DIIODO-
O-(4-HYDROXYPHENYL)-3,5-DIIODO-L-TYROSINE
diiodothyronine
3-5-diiodo-L-thyronine crystalline
3,5-diiodothyronine
3-[4-p-[Hydroxyphenoxy]-3,5-diiodophenyl] alanine
3,5-Diiodi-L-thyronine
3,5-DIIODO-L-THYRONINE 98%
3,5-Diiodo-4-(4-hydroxyphenoxy)-L-phenylalanine, O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine
3,5-Diiodo-O-(4-hydroxyphenyl)-L-tyrosine
L-Diiodothyronine | [EINECS(EC#)]
213-867-7 | [Molecular Formula]
C15H13I2NO4 | [MDL Number]
MFCD00064987 | [Molecular Weight]
525.08 | [MOL File]
1041-01-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
255-260 °C (dec.)
| [Boiling point ]
559.4±50.0 °C(Predicted) | [density ]
2.095±0.06 g/cm3(Predicted) | [vapor pressure ]
0.011Pa at 45℃ | [storage temp. ]
2-8°C
| [solubility ]
Acidic Alcohol (Slightly), Aqueous Base (Slightly) | [form ]
Solid | [pka]
2.15±0.30(Predicted) | [color ]
White to Light Brown | [Water Solubility ]
20.147mg/L at 20℃ | [Usage]
Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism. | [BRN ]
2707891 | [Stability:]
Hygroscopic | [InChIKey]
ZHSOTLOTTDYIIK-ZDUSSCGKSA-N | [LogP]
1.1 at 25℃ | [CAS DataBase Reference]
1041-01-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
8 | [HS Code ]
29225090 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism. | [Definition]
ChEBI:(2S)-2-amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid is a phenylalanine derivative. | [Flammability and Explosibility]
Notclassified | [Pharmacology]
3,5-Diiodo-L-thyronine is a thyroid hormone with a l-thyroxine-like activity. | [storage]
-20°C | [Purification Methods]
Recrystallise it from EtOH. [Chambers et al. J Chem Soc 3424 1949, Beilstein 14 II 226, 14 III 1565, 14 IV 2372.] |
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