| Identification | More | [Name]
Sodium levothyroxine | [CAS]
25416-65-3 | [Synonyms]
3-[4-4-HYDROXY-3,5-DIIODOPHENOXY-3,5-DIIODOPHENYL]-L-ALANINE
3-[4-4-HYDROXY-3,5-DIIODOPHENOXY-3,5-DIIODOPHENYL]-L-ALANINE, HYDRATE
L-THYROXINE SODIUM, HYDRATE
L-THYROXINE SODIUM SALT
L-THYROXINE SODIUM SALT, HYDRATE
sodium (2s)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate
sodium 4-o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosine
SODIUM LEVOTHYROXINE
SODIUM LEVOTHYROXINE, HYDRATE
L-THYROXIN SODIUM
LEVOTHYROXINESODIUM,HYDRATE,BP
3,3μ,5,5μ-Tetraiodo-L-thyronine hydrate monosodium salt, Sodium O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine hydrate
Levothyroxine sodium hydrate | [EINECS(EC#)]
200-221-4 | [Molecular Formula]
C15H10I4NNaO4 | [MDL Number]
MFCD06408007 | [Molecular Weight]
798.85 | [MOL File]
25416-65-3.mol |
| Chemical Properties | Back Directory | [Appearance]
almost white to beige or | [Melting point ]
207 °C | [alpha ]
16 º (c=2,1M HCl/alcohol 1/4) | [storage temp. ]
Store at 0-5°C | [solubility ]
Very slightly soluble in water, slightly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides. | [form ]
Liquid | [color ]
Clear yellow to yellow-greenish | [Water Solubility ]
0.15 g/L (25 ºC) | [Stability:]
Hygroscopic | [Major Application]
agriculture
environmental | [InChI]
InChI=1/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/s3 | [InChIKey]
YDTFRJLNMPSCFM-ZLBVLXFENA-M | [SMILES]
C1(=CC(=C(O)C(I)=C1)I)OC1=C(I)C=C(C[C@H](N)C([O-])=O)C=C1I.[Na+] |&1:16,r| | [CAS DataBase Reference]
25416-65-3(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Uses]
L-Thyroxine sodium hydrate is a useful research chemical. Its free form Thyroxine (T425600) is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS08 | [Signal word ]
Danger | [Hazard statements ]
H372 | [Precautionary statements ]
P260-P264-P270-P314-P501 | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3 | [HS Code ]
29379000 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
STOT RE 1 |
| Hazard Information | Back Directory | [Chemical Properties]
almost white to beige or | [Definition]
ChEBI: Levothyroxine sodium hydrate is an organic molecular entity. | [Brand name]
Levo-T (Alara);
Levolet (Vintage); Levothroid (Lloyd); Levoxyl (Jones);
Novothyrox (Genpharm); Synthroid (Abbott); Unithroid
(Stevens J). |
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Spectrum Chemical Manufacturing Corp.
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