| Identification | Back Directory | [Name]
METHYLMALONYL COENZYME A LITHIUM | [CAS]
104809-02-1 | [Synonyms]
MM-CoA
Methylmalonyl-CoA
METHYLMALONYL COENZYME A LITHIUM
METHYLMALONYL COENZYME A TETRALITHIUM &
α-methylmalonyl coenzyme a tetralithium salt
coenzyme A methylmalonyl derivative, lithium salt
methylmalonyl coenzyme a tetralithium salt hydrate
Methylmalonyl coenzyme A hydrate tetralithium salt
coenzyme A methylmalonyl derivative, tetralithium hydrate
Methylmalonyl coenzyme A tetralithium salt hydrate >=90% (HPLC)
3-[2-[3-[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]aminopropanoylamino]ethylsulfanyl]-2-methyl-3-oxo-propanoic acid | [Molecular Formula]
C25H41LiN7O19P3S | [MDL Number]
MFCD10567443 | [MOL File]
104809-02-1.mol | [Molecular Weight]
875.55 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
H2O: 50 mg/mL, clear, colorless | [form ]
Solid | [color ]
Off-white to light yellow | [InChIKey]
ANDKBBZIPFWODN-WLVKLPLXSA-J |
| Hazard Information | Back Directory | [Uses]
Methylmalonyl coenzyme A (CoA) has been used in the preparation of the calibration curve in ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS). It has also been used in the measurement of methylmalonyl-CoA mutase and methylmalonyl-CoA epimerase activity. | [Biochem/physiol Actions]
Methylmalonyl coenzyme A (CoA) is a catabolite of odd-chain fatty acids, cholesterol and few amino acids like valine, isoleucine, methionine, threonine. It is produced by the activity of the enzyme propionyl-CoA carboxylase(PCC). Methylmalonyl coenzyme A (CoA) is converted to succinyl-CoA by the methylmalonyl-CoA mutase (MCM) and vitamin B12 as the cofactor. Either a low MCM activity or an altered metabolism of vitamin B12 causes the inherited metabolic disease methylmalonic acidemia (MMA). |
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