ChemicalBook--->CAS DataBase List--->609-36-9

609-36-9

609-36-9 Structure

609-36-9 Structure
IdentificationMore
[Name]

DL-Proline
[CAS]

609-36-9
[Synonyms]

DL-2-PYRROLIDINECARBOXYLIC ACID
DL-PROLINE
DL-PYRROLIDINE-2-CARBOXYLIC ACID
H-DL-PRO-OH
H-DL-PYRD(2)-OH
LABOTEST-BB LTBB000673
(+/-)-PYRROLIDINE-2-CARBOXYLIC ACID
PYRROLIDINE-2-CARBOXYLIC ACID
Proline, DL-
H-DL-Pro-OH~(+/-)-Pyrrolidine-2-carboxylic acid
ProlinePyrrolidinecarboxylicacid
DL-Proline,99%
(n)-pyrrolidine-2-carboxylic acid
DL-Prolin
(R,S)-Pyrrolidine-2-carboxylic acid
(RS)-Proline
rac-(2R*)-Pyrrolidine-2-carboxylic acid
rac-(2R*)-Pyrrolidine-2β*-carboxylic acid
[EINECS(EC#)]

210-189-3
[Molecular Formula]

C5H9NO2
[MDL Number]

MFCD00005250
[Molecular Weight]

115.13
[MOL File]

609-36-9.mol
Chemical PropertiesBack Directory
[Appearance]

white to off-white crystalline powder
[Melting point ]

208 °C (dec.) (lit.)
[Boiling point ]

215.41°C (rough estimate)
[density ]

1.1808 (rough estimate)
[refractive index ]

1.4538 (estimate)
[storage temp. ]

Store at RT.
[solubility ]

Methanol, Water
[form ]

Crystalline Powder
[pka]

2.35±0.20(Predicted)
[color ]

White to off-white
[Water Solubility ]

SOLUBLE
[Merck ]

14,7780
[BRN ]

80809
[Major Application]

peptide synthesis
[Cosmetics Ingredients Functions]

SKIN CONDITIONING
HAIR CONDITIONING
[InChI]

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
[InChIKey]

ONIBWKKTOPOVIA-UHFFFAOYSA-N
[SMILES]

OC(=O)C1CCCN1
[CAS DataBase Reference]

609-36-9(CAS DataBase Reference)
[NIST Chemistry Reference]

DL-Proline(609-36-9)
[EPA Substance Registry System]

609-36-9(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P302+P352-P304+P340-P305+P351+P338-P312-P321
[Hazard Codes ]

Xn
[Risk Statements ]

R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[F ]

3-10
[TSCA ]

Yes
[HS Code ]

29339900
[Storage Class]

11 - Combustible Solids
Raw materials And Preparation ProductsBack Directory
[Raw materials]

L-Proline-->Proline, 1-(trichloroacetyl)-, methyl ester (9CI)-->(Acetylamino)(3-oxopropyl)malonic acid diethyl ester-->Pyrrole-2-carboxylic acid-->Methyl 2,5-Dibromopentanoate-->Proline, 1-hydroxy--->D-Proline
[Preparation Products]

H-DL-Pro-OMe HCl-->Ac-DL-Pro-OH-->1-Methylpyrrolidine-2-methanol-->2-Hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester-->1-[4-(Methylsulfonyl)-2-nitrophenyl]pyrrolidine-2-carboxylic acid-->1-[(4-methylphenyl)methyl]pyrrolidine-->1-Benzoyl-pyrrolidine-2-carboxylic acid
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

DL-Proline(609-36-9).msds
Hazard InformationBack Directory
[Chemical Properties]

white to off-white crystalline powder
[Uses]

DL-Proline is the racemic mixture of both L-Proline (P755995) and D-Proline (P755990).
[Definition]

ChEBI: An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2.
[reaction suitability]

reaction type: solution phase peptide synthesis
[Synthesis]

Input 100g of glacial acetic acid into the reaction kettle, and then input 100g of L-proline under stirring to obtain the reaction solution. After the reaction solution was stirred and warmed to 70-75°C, it was kept warm and stirred for 3h to make the

Spectrum DetailBack Directory
[Spectrum Detail]

DL-Proline(609-36-9)MS
DL-Proline(609-36-9)1HNMR
DL-Proline(609-36-9)13CNMR
DL-Proline(609-36-9)IR1
DL-Proline(609-36-9)IR2
DL-Proline(609-36-9)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

DL-Proline, 99%(609-36-9)
[Alfa Aesar]

DL-Proline, 99%(609-36-9)
[TCI AMERICA]

DL-Proline,>99.0%(T)(609-36-9)
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