| Identification | More | [Name]
2,3-Cyclohexeno pyridine | [CAS]
10500-57-9 | [Synonyms]
2,3-CYCLOHEXENO PYRIDINE
5,6,7,8-TETRAHYDROQUINOLINE
quinoline,5,6,7,8-tetrahydro-
2,3-CYCLOHEXANO PYRIDINE
5,6,7,8-Tetrahydroquinoline97%
5,6,7,8-Tetrahydroquinoline 97%
5,6,7,8-TETRAHYDROQUINOLINE 98.0%MIN
2,3-CYCLOHEXANO PYRIDINE 5,6,7,8-TETRAHYDRO-QUINOLINE
5,6,7,8-TETRAHYDROQUINOLINE(2,3-CYCLOHEXANOPYRIDINE)
5,6,7,8-Tetrahydroquinoline ,98% | [EINECS(EC#)]
234-030-2 | [Molecular Formula]
C9H11N | [MDL Number]
MFCD00006734 | [Molecular Weight]
133.19 | [MOL File]
10500-57-9.mol |
| Chemical Properties | Back Directory | [Boiling point ]
238°C | [density ]
1,08 g/cm3 | [refractive index ]
1.5420 to 1.5450 | [Fp ]
90°C | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Slightly), DMSO (Sparingly) Methanol (Slightly) | [form ]
Oil | [pka]
6.30±0.20(Predicted) | [color ]
Colourless | [Specific Gravity]
1.0341.0304 (20/4℃) | [Detection Methods]
GC,NMR | [InChI]
InChI=1S/C9H11N/c1-2-6-9-8(4-1)5-3-7-10-9/h3,5,7H,1-2,4,6H2 | [InChIKey]
YQDGQEKUTLYWJU-UHFFFAOYSA-N | [SMILES]
N1C2=C(CCCC2)C=CC=1 | [CAS DataBase Reference]
10500-57-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Quinoline, 5,6,7,8-tetrahydro-(10500-57-9) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335-H412 | [Precautionary statements ]
P280-P301+P310-P261 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37/39:Wear suitable gloves and eye/face protection . | [REACH Registrations]
Active | [HS Code ]
29334900 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless to light yellow liquid | [Uses]
5,6,7,8-Tetrahydroquinoline can be used to prevent and treat of hyperlipemia. | [Synthesis]
5,6,7,8-Tetrahydroquinoline is prepared by the reaction of pyridine and 1,4-dichlorobutane. The specific synthesis steps are as follows:
At 25℃ and an inert atmosphere,Compound 2 (2.67 g, 21.02 mmol) was added to a suspension of aluminum chloride (0.20 g, 1.5 mmol) in pyridine (10 mL). After stirring the obtained orange solution for 24 hours, It was poured into an ice water mixture (50 g) and extracted with ethyl acetate (50 mL).The organic layer was separated and washed sequentially with water (50 mL). The organic layer was washed with saturated sodium bicarbonate solution (50 mL) and brine (50 mL). It was then dried over NaSO4 and concentrated in vacuo. The yellow oil was subjected to flash chromatography on silica gel (eluent: hexane), Obtaining 5,6,7,8-tetrahydroquinoline, 2.66 g, yield 95%.
 | [References]
[1] A. Curran, R. Shepherd. “5,6,7,8-Tetrahydroquinolines. Part III. Synthesis of 5,6,7,8-tetrahydroquinoline-8-thiocarboxamides.” Journal of The Chemical Society-perkin Transactions 1 11 1 (1976): 983–986.
[2] T. Kusumi, H. Kakisawa, K. Yoneda. “A Convenient Synthesis of 5,6,7,8-Tetrahydroquinoline.” Synthesis-Stuttgart 2013 1 (1979): 221–223.
[3] T. KUSUMI, H. KAKISAWA, K. YONEDA. “ChemInform Abstract: A CONVENIENT SYNTHESIS OF 5,6,7,8-TETRAHYDROQUINOLINE.” ChemInform 10 28 (1979). |
| Spectrum Detail | Back Directory | [Spectrum Detail]
5,6,7,8-Tetrahydroquinoline(10500-57-9)MS
5,6,7,8-Tetrahydroquinoline(10500-57-9)1HNMR
5,6,7,8-Tetrahydroquinoline(10500-57-9)13CNMR
5,6,7,8-Tetrahydroquinoline(10500-57-9)IR1
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J & K SCIENTIFIC LTD.
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Energy Chemical
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Jia Xing Isenchem Co.,Ltd
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