Identification | More | [Name]
2-Chloro-3-hydroxypyridine | [CAS]
6636-78-8 | [Synonyms]
2-CHLORO-3-HYDROXYPYRIDINE 2-CHLORO-3-PYRIDINOL 2-CHLOROPYRIDIN-3-OL 2-CHLORO-PYRIDINE-3-OL 2-chloro-3-pyridino 3-Pyridinol, 2-chloro- 2-chloro-3-hdyroxypyridine 2-CHLORO-3-HYDROXYL PYRIDINE 3-Pyridinol,2-chloro-(6CI,8CI,9CI) 2-CHLORO-3-HYDROXYPYRIDINE 2-CHLORO-PYRIDIN-3-OL 2-CHLORO-3-HYDROXYPYRIDINE (2-CHLORO-3-PYRIDINOL) 2-Chloro-3-pyridinol 2-Chloro-3-hydroxypyridine 3-Hydroxy-2-chloropyridine | [EINECS(EC#)]
229-635-3 | [Molecular Formula]
C5H4ClNO | [MDL Number]
MFCD00006235 | [Molecular Weight]
129.54 | [MOL File]
6636-78-8.mol |
Chemical Properties | Back Directory | [Appearance]
light beige powder | [Melting point ]
170-172 °C (lit.) | [Boiling point ]
316.2±22.0 °C(Predicted) | [density ]
1.2309 (rough estimate) | [refractive index ]
1.4510 (estimate) | [storage temp. ]
Inert atmosphere,2-8°C | [form ]
Powder | [pka]
4.32±0.10(Predicted) | [color ]
Light beige | [BRN ]
2216 | [InChI]
InChI=1S/C5H4ClNO/c6-5-4(8)2-1-3-7-5/h1-3,8H | [InChIKey]
RSOPTYAZDFSMTN-UHFFFAOYSA-N | [SMILES]
C1(Cl)=NC=CC=C1O | [CAS DataBase Reference]
6636-78-8(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Chloro-3-pyridinol(6636-78-8) |
Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S37/39:Wear suitable gloves and eye/face protection . S24/25:Avoid contact with skin and eyes . S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
UU7707000
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29333990 |
Hazard Information | Back Directory | [Chemical Properties]
light beige powder | [Uses]
2-Chloro-3-hydroxypyridine has been used in the preparation of 3-hydroxypyridine-2( 1 H)-selone. It has also been used in the synthesis of all four possible benzo[4,5]furopyridine tricyclic heterocycles: benzo[4,5]furo[2,3-b]pyridine, benzo[4,5]furo[2,3-c]pyridine, benzo[4,5]furo[3,2-c]pyridine, and benzo[4,5]furo[3,2-b]pyridine. the synthesis involves α and γ-activation of chloropyridines, as well as palladium-mediated reactions. |
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