ChemicalBook--->CAS DataBase List--->105047-45-8

105047-45-8

105047-45-8 Structure

105047-45-8 Structure
IdentificationMore
[Name]

FMOC-LYS-OH
[CAS]

105047-45-8
[Synonyms]

FMOC-L-LYSINE
FMOC-L-LYS-OH
FMOC-LYS-OH
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-LYSINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LYSINE
N-ALPHA-FMOC-L-LYSINE
[Molecular Formula]

C21H24N2O4
[MDL Number]

MFCD00038539
[Molecular Weight]

368.43
[MOL File]

105047-45-8.mol
Chemical PropertiesBack Directory
[Melting point ]

26.8 °C
[Boiling point ]

607.6±55.0 °C(Predicted)
[density ]

1.245±0.06 g/cm3(Predicted)
[storage temp. ]

Store at 0°C
[form ]

Solid
[pka]

3.81±0.21(Predicted)
[color ]

White to yellow
[InChIKey]

YRKFMPDOFHQWPI-IBGZPJMESA-N
[SMILES]

C(O)(=O)[C@H](CCCCN)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
[CAS DataBase Reference]

105047-45-8(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H332-H335
[Precautionary statements ]

P261-P280-P305+P351+P338
[Safety Statements ]

24/25
[HS Code ]

29225090
Hazard InformationBack Directory
[Chemical Properties]

White to off-white powder
[Uses]

Nα-Fmoc-L-lysine is an N-Fmoc-protected form of L-Lysine (L468895). L-Lysine is an essential amino acid for humans, with a suggested intake of 5-8 grams per day. L-Lysine can be found in a variety of food, such as eggs and quinoa, but is also mass produced by microbial fermentation. L-Lysine is also used as therapy to treat recurrent herpes simplex infections.
[reaction suitability]

reaction type: Fmoc solid-phase peptide synthesis
[Synthesis]

FMOC-lysine can be produced by a one-step reaction using lysine and 9-fluorenylmethyl chloroformate as starting materials in the following steps:

A methylene chloride solution of lysine was added to a clean and dry round-bottomed flask, cooled di

Spectrum DetailBack Directory
[Spectrum Detail]

FMOC-LYS-OH(105047-45-8)1HNMR
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