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10578-75-3

10578-75-3 Structure

10578-75-3 Structure
IdentificationBack Directory
[Name]

2-(BENZYLOXY)-1-ETHANAMINE HYDROCHLORIDE
[CAS]

10578-75-3
[Synonyms]

2-(Benzyloxy)-1-ethaneamineHCl
2-(Benzyloxy)-1-ethanamine, HCl
2-benzoxyethylamine hydrochloride
AMINOETHYLBENZYL ETHER HYDROCHLORIDE
Aminoethylbenzyletherhydrochloride90%
2-(benzyloxy)ethanamine hydrochloride
[2-(benzyloxy)ethyl]amine hydrochloride
2-phenylmethoxyethanamine hydrochloride
2-Aminoethylbenzyletherhydrochloride90%
2-Aminoethyl benzyl ether hydrochloride
2-(benzyloxy)ethan-1-amine hydrochloride
2-(BENZYLOXY)-1-ETHANAMINE HYDROCHLORIDE
2-(Benzyloxy)-1-ethaneaminehydrochloride
Aminoethylbenzyl ether hydrochloride 90%
2-(phenylmethoxy)-ethylamine hydrochloride
2-Aminoethyl benzyl ether hydrochloride 90%
EthanaMine, 2-(phenylMethoxy)-, hydrochloride
[Molecular Formula]

C9H14ClNO
[MDL Number]

MFCD06411550
[MOL File]

10578-75-3.mol
[Molecular Weight]

187.67
Chemical PropertiesBack Directory
[Melting point ]

142 °C
[storage temp. ]

Sealed in dry,Room Temperature
[form ]

liquid
[color ]

Colorless
[InChI]

InChI=1S/C9H13NO.ClH/c10-6-7-11-8-9-4-2-1-3-5-9;/h1-5H,6-8,10H2;1H
[InChIKey]

AFQMWBUNDONXED-UHFFFAOYSA-N
[SMILES]

C(C1C=CC=CC=1)OCCN.Cl
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312-H315-H319-H335
[Precautionary statements ]

P271-P260-P280
[Hazard Codes ]

Xi,Xn
[Risk Statements ]

22-36-43
[Safety Statements ]

26-36
[Hazard Note ]

Harmful
[HazardClass ]

IRRITANT
[HS Code ]

2922390090
Hazard InformationBack Directory
[Uses]

2-Benzyloxyethylamine Hydrochloride is used to synthesize single and double-chain fluorocarbon and hydrocarbon galactosyl amphiphiles with anti-HIV-1 activities.
[Synthesis]

tert-butyl 2-(benzyloxy)ethylcarbamate

634925-24-9

2-(BENZYLOXY)-1-ETHANAMINE HYDROCHLORIDE

10578-75-3

General procedure for the synthesis of 2-benzyloxyethylamine hydrochloride from the compound (CAS: 634925-24-9): to a solution of ether (10 mL) of the product obtained in step 2 (4 g, 15.93 mmol) was slowly added an ether solution (20 mL) of 4N HCl. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was filtered and the filter cake was washed with hexane. Subsequently, the product was dried under vacuum to afford 2-benzyloxyethylamine hydrochloride in the form of an off-white solid (2 g, 83% yield). The structure of the product was confirmed by 1H-NMR (400 MHz, DMSO-d6): δ 3.01 (t, J = 5.20 Hz, 2H), 3.63 (t, J = 5.60 Hz, 2H), 4.54 (s, 2H), 7.35-7.36 (m, 5H), 8.01 (bs, 3H).

[References]

[1] Patent: WO2015/27021, 2015, A1. Location in patent: Page/Page column 87 ;88
[2] Carbohydrate Research, 2000, vol. 327, # 3, p. 223 - 260
[3] Patent: US2004/10007, 2004, A1. Location in patent: Page 64-65; 82
Spectrum DetailBack Directory
[Spectrum Detail]

2-(BENZYLOXY)-1-ETHANAMINE HYDROCHLORIDE(10578-75-3)1HNMR
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