| Identification | Back Directory | [Name]
2-(BENZYLOXY)-1-ETHANAMINE HYDROCHLORIDE | [CAS]
10578-75-3 | [Synonyms]
2-(Benzyloxy)-1-ethaneamineHCl 2-(Benzyloxy)-1-ethanamine, HCl 2-benzoxyethylamine hydrochloride AMINOETHYLBENZYL ETHER HYDROCHLORIDE Aminoethylbenzyletherhydrochloride90% 2-(benzyloxy)ethanamine hydrochloride [2-(benzyloxy)ethyl]amine hydrochloride 2-phenylmethoxyethanamine hydrochloride 2-Aminoethylbenzyletherhydrochloride90% 2-Aminoethyl benzyl ether hydrochloride 2-(benzyloxy)ethan-1-amine hydrochloride 2-(BENZYLOXY)-1-ETHANAMINE HYDROCHLORIDE 2-(Benzyloxy)-1-ethaneaminehydrochloride Aminoethylbenzyl ether hydrochloride 90% 2-(phenylmethoxy)-ethylamine hydrochloride 2-Aminoethyl benzyl ether hydrochloride 90% EthanaMine, 2-(phenylMethoxy)-, hydrochloride | [Molecular Formula]
C9H14ClNO | [MDL Number]
MFCD06411550 | [MOL File]
10578-75-3.mol | [Molecular Weight]
187.67 |
| Chemical Properties | Back Directory | [Melting point ]
142 °C | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
liquid | [color ]
Colorless | [InChI]
InChI=1S/C9H13NO.ClH/c10-6-7-11-8-9-4-2-1-3-5-9;/h1-5H,6-8,10H2;1H | [InChIKey]
AFQMWBUNDONXED-UHFFFAOYSA-N | [SMILES]
C(C1C=CC=CC=1)OCCN.Cl |
| Hazard Information | Back Directory | [Uses]
2-Benzyloxyethylamine Hydrochloride is used to synthesize single and double-chain fluorocarbon and hydrocarbon galactosyl amphiphiles with anti-HIV-1 activities. | [Synthesis]
General procedure for the synthesis of 2-benzyloxyethylamine hydrochloride from the compound (CAS: 634925-24-9): to a solution of ether (10 mL) of the product obtained in step 2 (4 g, 15.93 mmol) was slowly added an ether solution (20 mL) of 4N HCl. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was filtered and the filter cake was washed with hexane. Subsequently, the product was dried under vacuum to afford 2-benzyloxyethylamine hydrochloride in the form of an off-white solid (2 g, 83% yield). The structure of the product was confirmed by 1H-NMR (400 MHz, DMSO-d6): δ 3.01 (t, J = 5.20 Hz, 2H), 3.63 (t, J = 5.60 Hz, 2H), 4.54 (s, 2H), 7.35-7.36 (m, 5H), 8.01 (bs, 3H). | [References]
[1] Patent: WO2015/27021, 2015, A1. Location in patent: Page/Page column 87 ;88 [2] Carbohydrate Research, 2000, vol. 327, # 3, p. 223 - 260 [3] Patent: US2004/10007, 2004, A1. Location in patent: Page 64-65; 82 |
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