| | Identification | More |  | [Name] 
 ORPHENADRINE HYDROCHLORIDE
 |  | [CAS] 
 341-69-5
 |  | [Synonyms] 
 BF 5930
 BG 5930
 BS 5930
 Mebedrol
 Mephenamin
 Brocasipal
 Mephenamine
 Brocadisipal
 mephenaminforte
 Mephenamin forte
 ORPHENADRINE HCL
 disipalhydrochloride
 Disipal hydrochloride
 orfenadrinhydrochloride
 Mefenamin hydrochloride
 mephenaminhydrochloride
 Mephenamin hydrochloride
 mephenaminehydrochloride
 Orfenadrin hydrochloride
 Mephenamine hydrochloride
 Orph·Nadrine hydrochloride
 Orphenedrine hydrochloride
 ORPHENADRINE HYDROCHLORIDE
 OrphenadrineHydrochloride>
 Orphenadrine hydrochloride,99%
 Orphenadrine hydrochloride CRS
 O-METHYLDIPHENHYDRAMINE HYDROCHLORIDE
 Orphenadrine hydrochloride >=98.0% (AT)
 ORPHENADRINE HYDROCHLORIDE ISO 9001:2015 REACH
 2-dimethylaminoethyl2-methylbenzhydryletherhydrochloride
 2-(PHENYL-O-TOLYLMETHOXY)ETHYLDIMETHYLAMINE HYDROCHLORIDE
 B-DIMETHYLAMINOETHYL 2-METHYLBENZHYDRYL ETHER HYDROCHLORIDE
 2-Dimethylaminoethyl 2-methylbenzhydryl ether hydrochloride
 N,N-DIMETHYL-2-(2-METHYLBENZHYDRYLOXY)-ETHYLAMINE HYDROCHLORIDE
 N,N-Dimethyl-2-(alpha-(o-tolyl)benzyloxy)ethylamine hydrochloride
 Ethylamine, N,N-dimethyl-2-(phenyl-(o-tolyl)methoxy)-, hydrochloride
 Ethylamine, N,N-dimethyl-2-(alpha-(o-tolyl)benzyloxy)-, hydrochloride
 n,n-dimethyl-2-(o-methyl-alpha-phenylbenzyloxy)ethylaminehydrochloride
 N,N-Dimethyl-2-(o-methyl-alpha-phenylbenzyloxy)ethylamine hydrochloride
 n,n-dimethyl-2-((o-methyl-alpha-phenylbenzyl)oxy)-ethylaminhydrochloride
 Ethanamine, N,N-dimethyl-2-[(2-methylphenyl)phenylmethoxy]-, hydrochloride
 Ethylamine, N,N-dimethyl-2-((o-methyl-alpha-phenylbenzyl)oxy)-, hydrochloride
 EthanaMine,N,N-diMethyl-2-[(2-Methylphenyl)phenylMethoxy]-, hydrochloride (1:1)
 o-Methyldiphenhydramine  hydrochloride,  N,N-Dimethyl-2-(2-methylbenzhydryloxy)ethylamine  hydrochloride,  β-Dimethylaminoethyl  2-methylbenzhydryl  ether  hydrochloride
 |  | [EINECS(EC#)] 
 206-435-4
 |  | [Molecular Formula] 
 C18H24ClNO
 |  | [MDL Number] 
 MFCD00012480
 |  | [Molecular Weight] 
 305.84
 |  | [MOL File] 
 341-69-5.mol
 | 
 | Safety Data | Back Directory |  | [Hazard Codes ] 
 Xn
 |  | [Risk Statements ] 
 R22:Harmful if swallowed.
 |  | [Safety Statements ] 
 S36:Wear suitable protective clothing .
 |  | [RIDADR ] 
 3249
 |  | [WGK Germany ] 
 3
 |  | [RTECS ] 
 KR6300000
 |  | [HazardClass ] 
 6.1(b)
 |  | [PackingGroup ] 
 III
 |  | [Safety Profile] 
 Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human systemic effects: mydriasis @updlaryd ilation), hallucinations, distorted perceptions, pulse rate increase, intracranial pressure increase. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl
 |  | [Toxicity] 
 LD50 oral in rat: 255mg/kg
 | 
 | Hazard Information | Back Directory |  | [General Description] 
 Odorless white or almost white crystalline powder.  pH (aqueous solution) about 5.5.  Bitter numbing taste.
 |  | [Reactivity Profile] 
 ORPHENADRINE HYDROCHLORIDE(341-69-5) is incompatible with strong oxidizers.
 |  | [Air & Water Reactions] 
 May be sensitive to prolonged exposure to light and air. Water soluble.
 |  | [Fire Hazard] 
 Flash point data for this chemical are not available; however, ORPHENADRINE HYDROCHLORIDE is probably combustible.
 |  | [Chemical Properties] 
 White or almost white, crystalline powder.
 |  | [Uses] 
 Antihistaminic;H1 antogonist
 |  | [Definition] 
 ChEBI: A hydrochloride comprising equimolar amounts of ophenadrine and hydrogen chloride.
 |  | [Biochem/physiol Actions] 
 Muscarinic receptor antagonist; H1 histamine receptor antagonist; muscle relaxant.  Orphenadrine has also been reported to inhibit the noradrenergic transporter and to block the NMDA receptor ion channel.
 |  | [Clinical Use] 
 Anti-muscarinic:
 Parkinsonism
 Drug induced extra-pyramidal symptoms
 |  | [Drug interactions] 
 Potentially hazardous interactions with other drugs
 None known
 |  | [Metabolism] 
 Orphenadrine is almost completely metabolised to at least 
8 metabolites in the liver.
 It is mainly excreted in the urine as metabolites and small 
amounts of unchanged drug
 | 
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                            | Company Name: | Ralington Pharma |  
                            | Tel: | +91-7948911722 +91-9687771722 |  
                            | Website: | www.ralingtonpharma.com |  |