1071676-04-4

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1071676-04-4 Structure

Identification	Back Directory
[Name] 6-Methoxyldihydrochelerythrine chloride
[CAS] 1071676-04-4
[Synonyms] Angoline hydrochloride 6-Methoxyldihydrochelerythrine chloride
[Molecular Formula] C22H22ClNO5
[MOL File] 1071676-04-4.mol
[Molecular Weight] 415.87

Hazard Information	Back Directory
[Uses] Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].
[References] [1] Jiawei Liu, et al. Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Phytomedicine. Jul-Aug 2014;21(8-9):1088-91. DOI:10.1016/j.phymed.2014.04.001

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