| Identification | Back Directory | [Name]
Sophocarpine | [CAS]
6483-15-4 | [Synonyms]
Sophocarpine
SOPHOCARPINE(RG)
13,14-Didehydromatridin-15-one
13,14-DidehydroMatridin-15-one, 9CI
Matridin-15-one, 13,14-didehydro-, monohydrate
Sophocarpine, 98%, from Sophora flavescens Aiton
1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 2,3,6,7,7a,8,13,13a,13b,13c-decahydro-, (7aS,13aR,13bR,13cS)- | [Molecular Formula]
C15H22N2O | [MOL File]
6483-15-4.mol | [Molecular Weight]
246.35 |
| Chemical Properties | Back Directory | [Melting point ]
54～55℃ | [Boiling point ]
170-210 °C(Press: 5 Torr) | [density ]
1.19±0.1 g/cm3(Predicted) | [solubility ]
DMSO: 2 mg/ml; Ethanol: 1 mg/ml * | [form ]
A crystalline solid | [pka]
9.59±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Sophocarpine is an intermediate in the synthesis of (+)-Matrine-d3 (M197872). (+)-Matrine-d3, is a labeled analogue of (+)-Matrine, an alkaloid compound extracted from the roots of Sophora species which maintain anti-inflammatory, anti-cancer and a host of other positive pharmacological effects. Apoptotic agent. | [IC 50]
PI3K |
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