| Identification | More | [Name]
PHENYLGLYOXAL MONOHYDRATE | [CAS]
1075-06-5 | [Synonyms]
2,2-DIHYDROXY-1-PHENYL-ETHANONE
BENZOYLFORMALDEHYDE MONOHYDRATE
PHENYLGLYOXAL
PHENYLGLYOXAL HYDRATE
PHENYLGLYOXAL MONOHYDRATE
P-PHENYLGLYOXAL MONOHYDRATE
2,2-dihydroxy-1-phenyl-ethanon
2,2-dihydroxy-acetophenon
2,2-dihydroxyacetophenone | [EINECS(EC#)]
214-036-1 | [Molecular Formula]
C8H8O3 | [MDL Number]
MFCD00149499 | [Molecular Weight]
152.15 | [MOL File]
1075-06-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
76-79 °C(lit.) | [Boiling point ]
142 °C125 mm Hg(lit.) | [density ]
1.1603 (rough estimate) | [refractive index ]
1.5120 (estimate) | [Fp ]
142°C/125mm | [storage temp. ]
2-8°C | [solubility ]
95% ethanol: soluble5%, clear to very slightly hazy, colorless to light yellow | [form ]
Powder | [pka]
10.97±0.41(Predicted) | [color ]
White to light yellow or pinkish | [Water Solubility ]
Partly miscible with water. | [BRN ]
1854721 | [CAS DataBase Reference]
1075-06-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
MD3260000
| [HS Code ]
2914.40.4000 | [Toxicity]
mouse,LD50,oral,500mg/kg (500mg/kg),Journal of Medicinal and Pharmaceutical Chemistry. Vol. 1, Pg. 365, 1959. |
| Hazard Information | Back Directory | [Uses]
Phenylglyoxal monohydrate was used to modify pig muscle carbonic anhydraseIII and as a specific reagent for arginine groups. It was also used to prepare pyrrolinone and furan derivatives and as as a chemiluminescent reagent for the determination of purines. | [Biochem/physiol Actions]
Phenylglyoxal is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties. | [storage]
Store at -20°C |
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