ChemicalBook--->CAS DataBase List--->11000-17-2

11000-17-2

11000-17-2 Structure

11000-17-2 Structure
IdentificationMore
[Name]

Vasopressin
[CAS]

11000-17-2
[Synonyms]

VASOPRESSIN
adh(hormone)
leiormone
pitressin
pituitrin
tonephin
vasophysin
1-[19-amino-13-butan-2-yl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[1-(carbamoylmethylcarbamoyl)-4-(diaminomethylideneamino)butyl]pyrrolidine-2-carboxamide
VASOPRESSIN ACETATE
VASOPRASSIN
Cys(1)-Tyr-Phe-Glu(NH2)-Asp(NH2)-Cys(1)-Pro-Xaa-Gly-NH2
Vasopressin Injection
[EINECS(EC#)]

200-050-5
[Molecular Formula]

C46H65N13O12S2
[MDL Number]

MFCD03839092
[Molecular Weight]

1056.22
[MOL File]

11000-17-2.mol
Chemical PropertiesBack Directory
[solubility ]

Methanol (Slightly), Water (Slightly)
[form ]

Lyophilized Powder
[color ]

White
[Water Solubility ]

Soluble in water (Miscible).
[Sequence]

Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6)
[Stability:]

Hygroscopic
[CAS DataBase Reference]

11000-17-2(CAS DataBase Reference)
Safety DataBack Directory
[Hazardous Substances Data]

11000-17-2(Hazardous Substances Data)
Hazard InformationBack Directory
[Uses]

Vasopressin is a peptide hormone that regulates the body’s retention of water. Vasopressin is an antidiurectic hormone.
[Veterinary Drugs and Treatments]

Vasopressin is used in veterinary medicine as a diagnostic agent and in the treatment of diabetes insipidus in small animals. In recent years, there has been significant interest in using vasopressin for treating shock syndromes in humans and animals. Ongoing research is being conducted.
In human medicine, vasopressin has been used to treat acute GI hemorrhage and to stimulate GI peristalsis. Vasopressin CRI is also being used for treatment of hypotensive septic patients unresponsive to conventional vasopressor. Prior to radiographic procedures, it has been used to dispel interfering gas shadows or help concentrate contrast media.
[in vivo]

Vasopressin (0.03-0.3 μg/kg; i.p.) potentiates corticotropin release provoked by exogenous corticoliberin and increases corticotropin secretion subsequent to body water loss[2].
Vasopressin (0.001-0.1 mg/kg; i.p.) potently increases adjacent lying, where rats meeting for the first time lie passively next to each other[3].

[IC 50]

Human Endogenous Metabolite
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