| Identification | Back Directory | [Name]
5H-Indeno[1,2-b]pyridin-5-one, 6,7-dimethoxy-4-methyl- | [CAS]
111316-33-7 | [Synonyms]
α-Glucosidase-IN-5
5H-Indeno[1,2-b]pyridin-5-one, 6,7-dimethoxy-4-methyl- | [Molecular Formula]
C15H13NO3 | [MOL File]
111316-33-7.mol | [Molecular Weight]
255.27 |
| Chemical Properties | Back Directory | [Melting point ]
137-138 °C(Solv: hexane (110-54-3)) | [Boiling point ]
472.8±45.0 °C(Predicted) | [density ]
1.261±0.06 g/cm3(Predicted) | [pka]
2.96±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
α-Glucosidase-IN-5 (compound 8) is a potent α-glucosidase inhibitor with an IC50 of 57.9 μM. α-Glucosidase-IN-5 has the potential for the research of diabetes mellitus[1]. | [References]
[1] Suthiphasilp V, et al. α-Glucosidase inhibitory and nitric oxide production inhibitory activities of alkaloids isolated from a twig extract of Polyalthia cinnamomea. Bioorg Med Chem. 2020 May 15;28(10):115462. DOI:10.1016/j.bmc.2020.115462 |
|
|