| Identification | Back Directory | [Name]
ALPHA-GUANIDINOGLUTARIC ACID | [CAS]
73477-53-9 | [Synonyms]
GGA
Guanidinoglutaricacid
alpha-Guanidinoglutaric
A-GUANIDINOGLUTARIC ACID
α-Guanidinoglutaric acid
ALPHA-GUANIDINOGLUTARIC ACID
2-Guanidinopentanedioic acid
(S)-(-)-2-GUANIDINOGLUTARIC ACID
(S)-(-)-2-GuanidinoglutaricAcid>
N-(AMINOIMINOMETHYL)-L-GLUTAMIC ACID
(S)-(-)-2-GUANIDINOGLUTARIC ACID 98+%
(S)-(-)-2-Guanidinoglutaric Acid
(2S)-2-(Diaminomethylideneamino)pentanedioic Acid | [Molecular Formula]
C6H11N3O4 | [MDL Number]
MFCD00270869 | [MOL File]
73477-53-9.mol | [Molecular Weight]
189.17 |
| Chemical Properties | Back Directory | [Boiling point ]
414.7±55.0 °C(Predicted) | [density ]
1.62±0.1 g/cm3(Predicted) | [refractive index ]
-20 ° (C=4, 2mol/L HCl) | [storage temp. ]
2-8°C | [solubility ]
PBS pH 7.2: >50 mg/ml | [form ]
White crystalline solid. | [pka]
3.28±0.10(Predicted) | [color ]
White to Almost white |
| Hazard Information | Back Directory | [Description]
GGA is a linear mixed-type inhibitor of nNOS having a Ki of 2.69 μM.1 It is normally present in small quantities in the cerebral cortex of cats with increased levels following seizure.1,2 | [Uses]
Linear mixed-type inhibitor of neuronal nitric oxide synthase (nNOS/NOS I). | [Definition]
ChEBI: N-Amidino-L-glutamate is a L-glutamic acid derivative. | [References]
[1] H Shiraga, et al. Convulsive activity of alpha-guanidinoglutaric acid and the possible involvement of 5-hydroxytryptamine in the alpha-guanidinoglutaric acid-induced seizure mechanism. J Neurochem. 1986 Dec;47(6):1832-6. DOI:10.1111/j.1471-4159.1986.tb13095.x |
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