| Identification | More | [Name]
(+)-Diisopinocampheyl chloroborane | [CAS]
112246-73-8 | [Synonyms]
(+)-B-CHLORODIISOPINOCAMPHENYLBORANE
(+)-B-CHLORODIISOPINOCAMPHEYLBORANE
(+)-B-DIISOPINOCAMPHEYL-CHLOROBORANE
(+)-BETA-CHLORODIISOPINOCAMPHEYLBORANE
(+)-Diisopinocampheylchloroborane
(+)-DIP CHLORIDE
(+)-DIP-CHLORIDE(TM)
(+)-IPC2BCL
(+)-beta-Chlorodiisopinocampheylborane (ca. 65% in n-hexane)
(+)-β-Chlorodiisopinocampheylborane
(+)-DIP-CHLORIDE, TYPICALLY 90-105%
(+)-DIP chloride[R]
(+)-Diisopinocampheylchloroborane, 1.8M solution in hexanes
(+)-DIP CHLORIDE 60-70% SOLUTION IN HEPTANE
(+)-B-Chlorodiisopinocampheylborane
(+)-Diisopinocampheyl chloroborane
(+)-DIP chloride
(+)-DIP-CHLORIDE IN HEPTANES, 2M SOLUTION
(+)-B-Chlorodiisopinocampheylborane (58% in Hexane, ca. 1.6mol/L) | [Molecular Formula]
C20H34BCl | [MDL Number]
MFCD00074808 | [Molecular Weight]
320.75 | [MOL File]
112246-73-8.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
53-55 °C(lit.)
| [Boiling point ]
369.6±25.0 °C(Predicted) | [density ]
0.91 | [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
sol in both polar and nonpolar aprotic solvents like diethyl ether, THF, methylene chloride, pentane, hexane, etc | [form ]
clear liquid | [color ]
Colorless to Almost colorless | [Usage]
(+)-Diisopinocampheyl chloroborane(112246-73-8) are used for high enantiselective asymmetric reduction of prochiral ketones and for the preparation of β-amino alcohols. | [InChI]
InChI=1S/C20H34BCl/c1-11-15-7-13(19(15,3)4)9-17(11)21(22)18-10-14-8-16(12(18)2)20(14,5)6/h11-18H,7-10H2,1-6H3/t11-,12-,13+,14+,15-,16-,17-,18-/m0/s1 | [InChIKey]
PSEHHVRCDVOTID-YYNWCRCSSA-N | [SMILES]
B(Cl)([C@H]1C[C@@]2([H])C[C@]([H])(C2(C)C)[C@@H]1C)[C@H]1C[C@@]2([H])C[C@]([H])(C2(C)C)[C@@H]1C | [CAS DataBase Reference]
112246-73-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R37:Irritating to the respiratory system. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [F ]
10-21 | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29319090 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
Both (+)- and (-)-DIP-chloride are used for asymmetric reduction of prochiral ketones and for the preparation of β-amino alcohols. | [Precautions]
(+)-Diisopinocampheyl chloroborane and its solutions are moisture and air sensitive. The reagent reacts instantaneously with water and protic solvents to liberate HCl. Containers of DIP-Chloride should be stored in the absence of moisture. Cans or bottles of DIP-Chloride should be flushed with N2 and kept tightly sealed to avoid contact of oxygen and moisture.
| [storage]
(+)-Diisopinocampheyl chloroborane should be crushed, transferred, or weighed only in glove bag or dry box under N2 atmosphere. The reagent can be stored for several years under N2 atmosphere below 25 °C.
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