| Identification | More | [Name]
(S)-N-Fmoc-3-(2-naphthyl)alanine | [CAS]
112883-43-9 | [Synonyms]
FMOC-2-NAL-OH
FMOC-3-(2-NAPHTHYL)-ALANINE
FMOC-3-(2-NAPHTHYL)-L-ALANINE
FMOC-ALA(2-NAPH)-OH
FMOC-ALA(2-NAPHTHYL)-OH
FMOC-ALA-BETA-(2-NAPHTHYL)-OH
FMOC-BETA-(2-NAPHTHYL)-L-ALANINE
FMOC-L-2NAL-OH
FMOC-L-2-NAPHTHYLALANINE
FMOC-L-3-(2-NAPHTHYL)-ALANINE
FMOC-L-3-(2-NAPTHYL)ALANINE
FMOC-L-NAL(2)
FMOC-NAL(2)-OH
N-(9-FLUORENYLMETHOXYCARBONYL)-2-NAPHTHYL-L-ALANINE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-3-(2-NAPHTHYL)-L-ALANINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-3-(2-NAPHTHYL)ALANINE
N-ALPHA-(9-FLUORENYLOXYCARBONYL)-L-3-(2-NAPHTHYL)ALANINE
N-ALPHA-FMOC-BETA-(2-NAPHTHYL)-L-ALANINE
RARECHEM BK PT 0099
(S)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-NAPHTHALEN-2-YL-PROPIONIC ACID | [Molecular Formula]
C28H23NO4 | [MDL Number]
MFCD00144886 | [Molecular Weight]
437.49 | [MOL File]
112883-43-9.mol |
| Chemical Properties | Back Directory | [Appearance]
white to slightly yellow powder | [Melting point ]
155 °C
| [Boiling point ]
549.64°C (rough estimate) | [density ]
1.2227 (rough estimate) | [refractive index ]
1.6290 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
DMF (Sparingly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
3.77±0.30(Predicted) | [color ]
White to Off-White | [Optical Rotation]
Consistent with structure | [Water Solubility ]
Slightly soluble in water. | [Major Application]
peptide synthesis | [InChIKey]
JYUTZJVERLGMQZ-SANMLTNESA-N | [SMILES]
C(C1C2=CC=CC=C2C2=CC=CC=C12)OC(=O)N[C@H](C(=O)O)CC1C=CC2C=CC=CC=2C=1 | [CAS DataBase Reference]
112883-43-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P302+P352-P304+P340-P305+P351+P338 | [Hazard Codes ]
Xi | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29242990 | [Storage Class]
11 - Combustible Solids |
| Questions and Answers (Q&A) | Back Directory | [Description]
(S)-N-Fmoc-3-(2-naphthyl) alanine is an Fmoc protected form of alanine. Fmoc protected amino acid is quite useful in the solid phase peptide synthesis. Fmoc can be easily removed with piperidine solution without disturbing the acid labile linker between the peptide and the resin. The Fmoc amino acid is also suitable to be analyzed by HPLC due to its high fluorescent activity. Studies have also shown that (S)-N-Fmoc-3-(2-naphthyl) alanine and related peptides have certain inhibitory effect on Staphylococcus virulence.
| [References]
https://www.alfa.com/en/fmoc-protected-compounds/?page=2
http://a2.rqiao.net/patents/US20030050248
|
| Hazard Information | Back Directory | [Chemical Properties]
white to slightly yellow powder | [Uses]
N-Fmoc-3-(2-naphthyl)-L-alanine is used as organic chemical synthesis intermediate. | [reaction suitability]
reaction type: Fmoc solid-phase peptide synthesis |
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