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112897-99-1

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112897-99-1 Structure

112897-99-1 Structure
IdentificationBack Directory
[Name]

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine
[CAS]

112897-99-1
[Synonyms]

DMT-Cr
5'-O-DMT-cytidine
5'-O-(4,4'-Dimethoxytrityl)cytidine
5'-O-(4,4'-dimethoxytrityl)-cytidine
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine
Cytidine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]-
[Molecular Formula]

C30H31N3O7
[MOL File]

112897-99-1.mol
[Molecular Weight]

545.58
Chemical PropertiesBack Directory
[Boiling point ]

742.535±70.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.34
[pka]

13.445±0.70(predicted)
Hazard InformationBack Directory
[Uses]

5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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