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1132709-16-0

1132709-16-0 Structure

1132709-16-0 Structure
IdentificationBack Directory
[Name]

Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
[CAS]

1132709-16-0
[Synonyms]

Bortizomib SR-OH
(1S,2R)-BortezoMib
Bortezomib (1R,2R)Isomer
Bortezomib (1S, 2R)-Isomer
(1S,2R)-Bortezomib Impurity
Bortezomib S,R-Isomer Impurity
Bortezomib impurities (R, S-isomer)
Bortezomib Impurity (1S,2R - Isomer)
Bortezomib impurity 2/(1S,2R)-Bortezomib
N-(2-Pyrazinecarbonyl)-D-phenylalanine-D-leucine boronic anhydride
(S)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butylboronic acid
(1s) - 3-methyl-1 - [(2R) - 1-oxo-3-phenyl-2 - [(pyrazinoyl) - amino] propyl] amino] butyl] boric acid
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
(1S,2R) BortezomibQ: What is (1S,2R) Bortezomib Q: What is the CAS Number of (1S,2R) Bortezomib Q: What is the storage condition of (1S,2R) Bortezomib Q: What are the applications of (1S,2R) Bortezomib
[Molecular Formula]

C19H25BN4O4
[MDL Number]

MFCD09749895
[MOL File]

1132709-16-0.mol
[Molecular Weight]

384.24
Chemical PropertiesBack Directory
[density ]

1.214±0.06 g/cm3(Predicted)
[pka]

9.66±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

(1S,3R)-Bortezomib is an diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway
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