| Identification | Back Directory | [Name]
2-Carboxybenzoyl Amlodipine | [CAS]
318465-73-5 | [Synonyms]
Amlodipine-8
Amlodipine EP Imp H
AMlodipine iMpurity H
AMlodipine EP IMpurity H
Amlodipine EP Impurity I
AMlodipine IMpurity H (EP)
2-Carboxybenzoyl Amlodipine
2-[[2-[[(4RS)-4-(2-Chlorophenyl)-3-
Amlodipine EP Impurity H：Amlodipine Impurity H
Amlodipine Impurity 8（Amlodipine EP Impurity H）
Amlodipine Impurity-H (EP) ( 2-Carboxybenzoyl Amlodipine)
2-(2-((4-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2
2-(2-((4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(Methoxycarbonyl)-6-Methyl-1,4-dihydropyridin-2-yl)Methoxy)ethylcarbaMoyl)benzoic acid
2-[[2-[(2-Carboxybenzoyl)aMino]ethoxy]Methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-Methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
3,5-Pyridinedicarboxylic acid, 2-[[2-[(2-carboxybenzoyl)amino]ethoxy]methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
2-[[2-[[(4RS)-4-(2-Chlorophenyl)-3-(ethoxycarbonyl)- 5-(Methoxycarbonyl)-6-Methyl-1,4-dihydropyridin-2-yl] Methoxy]ethyl]-carbaMoyl]benzoic Acid
Amlodipine impurity 8/Amlodipine EP Impurity H/2-Carboxybenzoyl Amlodipine/2-[[2-[(2-Carboxybenzoyl)amino]ethoxy]methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester | [EINECS(EC#)]
608-671-7 | [Molecular Formula]
C28H29ClN2O8 | [MDL Number]
MFCD21363416 | [MOL File]
318465-73-5.mol | [Molecular Weight]
556.99 |
| Chemical Properties | Back Directory | [Melting point ]
160-162°C | [Boiling point ]
727.6±60.0 °C(Predicted) | [density ]
1.305±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
3.49±0.36(Predicted) | [color ]
White to Off-White | [PH]
4.94 at 27.1℃ and 1000g/L | [Major Application]
pharmaceutical small molecule | [InChIKey]
IAYRABGXHCLELQ-UHFFFAOYSA-N | [SMILES]
C1(COCCNC(=O)C2=CC=CC=C2C(O)=O)NC(C)=C(C(OC)=O)C(C2=CC=CC=C2Cl)C=1C(OCC)=O | [LogP]
23 at 25℃ |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Chronic 3
Skin Sens. 1B
STOT RE 2 Oral |
| Hazard Information | Back Directory | [Uses]
As Amlodipine Besilate (A633500) impurity, 2-Carboxybenzoyl AMlodipine can be used in the process for preparing Amlodipine benzenesulfonate.
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