ChemicalBook--->CAS DataBase List--->114667-74-2

114667-74-2

114667-74-2 Structure

114667-74-2 Structure
IdentificationBack Directory
[Name]

BU-E 75
[CAS]

114667-74-2
[Synonyms]

BU-E 75
Guanidine, N-[3-(3,4-difluorophenyl)-3-(2-pyridinyl)propyl]-N'-[3-(1H-imidazol-5-yl)propyl]-
[Molecular Formula]

C21H24F2N6
[MDL Number]

MFCD00885523
[MOL File]

114667-74-2.mol
[Molecular Weight]

398.45
Hazard InformationBack Directory
[Description]

BU-E 75 is a histamine H2 agonist.
[Uses]

BU-E-75 is a guanidine-type H2 receptor agonist that exhibits antagonism at postsynaptic α-adrenoceptors, which can relax the noradrenaline-precontracted vessels[1].
[References]

[1] Bungardt E, et al. Histamine H1 receptors mediate vasodilation in guinea-pig ileum resistance vessels: characterization with computer-assisted videomicroscopy and new selective agonists. Eur J Pharmacol. 1992 Oct 6;221(1):91-8. DOI:10.1016/0014-2999(92)90776-z
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