| Identification | More | [Name]
BOC-L-4-Trifluoromethylphe | [CAS]
114873-07-3 | [Synonyms]
4-(TRIFLUOROMETHYL)-L-PHENYLALANINE, BOC PROTECTED
Benzyloxycarbonyl-L-4-trifluoromethylphenylalanine
BOC-4-(TRIFLUOROMETHYL)-L-PHENYLALANINE
BOC-L-4-TRIFLUOROMETHYLPHE
BOC-L-4-TRIFLUOROMETHYLPHENYLALANINE
BOC-L-PHE(4-TRIFLUOROMETHYL)-OH
BOC-PHE(4-CF 3)-OH
L-4-(TRIFLUOROMETHYL)PHENYLALANINE, BOC PROTECTED
N-ALPHA-T-BUTOXYCARBONYL-L-(4-TRIFLUOROMETHYLPHENYL)ALANINE
N-BOC-4-(TRIFLUOROMETHYL)-L-PHENYLALANINE
RARECHEM BK PT 0140
(S)-2-TERT-BUTOXYCARBONYLAMINO-3-(4-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID
BOC-L-PHE(4-CF3)-OH
4-(Trifluoromethyl)-L-phenylalanine,N-BOCprotected
(S)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)propanoic acid
Boc-L-4-Trifluoromethyl-phe-OH | [Molecular Formula]
C15H18F3NO4 | [MDL Number]
MFCD00792407 | [Molecular Weight]
333.3 | [MOL File]
114873-07-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
118-137°C | [Boiling point ]
431.4±45.0 °C(Predicted) | [density ]
1.271±0.06 g/cm3(Predicted) | [storage temp. ]
Keep Cold | [form ]
powder to crystal | [pka]
3.76±0.10(Predicted) | [color ]
White to Almost white | [Optical Rotation]
[α]20/D +5.4±0.7°, c = 1% in methanol | [BRN ]
5617499 | [Major Application]
peptide synthesis | [InChI]
1S/C15H18F3NO4/c1-14(2,3)23-13(22)19-11(12(20)21)8-9-4-6-10(7-5-9)15(16,17)18/h4-7,11H,8H2,1-3H3,(H,19,22)(H,20,21)/t11-/m0/s1 | [InChIKey]
SMVCCWNHCHCWAZ-NSHDSACASA-N | [SMILES]
CC(C)(C)OC(=O)N[C@@H](Cc1ccc(cc1)C(F)(F)F)C(O)=O | [CAS DataBase Reference]
114873-07-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [WGK Germany ]
3
| [Hazard Note ]
Harmful/Irritant/Keep Cold | [HS Code ]
2924297099 | [Storage Class]
13 - Non Combustible Solids |
| Hazard Information | Back Directory | [Uses]
N-(tert-Butoxycarbonyl)-4-trifluoromethyl-L-phenylalanine is a useful pharmaceutical intermediate. It is used in the preparation of ring substituted phenylalanines and tryptophans. Also Used in the preparation of proline derivatives with inhibitory action against dipeptidyl peptidase IV. | [reaction suitability]
reaction type: Boc solid-phase peptide synthesis |
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