| Identification | More | [Name]
4-(4-Ethylpiperazin-1-ly)aniline | [CAS]
115619-01-7 | [Synonyms]
4-(4-ETHYLPIPERAZIN-1-YL)ANILINE
4-(4-ETHYL-PIPERAZIN-1-YL)-PHENYLAMINE
4-(4-ETHYLPIPERAZINO)ANILINE
AKOS B021943
AKOS BB-8659
ART-CHEM-BB B021943
TIMTEC-BB SBB007132
4-(4-ETHYLPIPERAZIN-1-YL)PHENYLAMINE, 95+%
4-(4-Ethylpiperazin-1-ly)aniline
4-(4-ethylpiperazino)phenylamine | [Molecular Formula]
C12H19N3 | [MDL Number]
MFCD00702246 | [Molecular Weight]
205.3 | [MOL File]
115619-01-7.mol |
| Hazard Information | Back Directory | [Synthesis]
General procedure: 1-ethyl-4-(4-nitrophenyl)piperazine (7.5 mmol) was dissolved in ethanol (50 mL) and 10% Pd/C catalyst (0.2 g) was added. The reaction mixture was stirred at room temperature and under hydrogen atmosphere for 9 hours. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration. The filtrate was concentrated under high vacuum to give the target product 4-(4-ethyl-1-piperazinyl)aniline. | [References]
[1] Journal of Medicinal Chemistry, 2011, vol. 54, # 20, p. 7066 - 7083
[2] Bulletin of the Korean Chemical Society, 2015, vol. 36, # 7, p. 1863 - 1873
[3] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 5, p. 1092 - 1099
[4] Patent: US2004/122237, 2004, A1. Location in patent: Page 180
[5] Patent: WO2006/420, 2006, A1. Location in patent: Page/Page column 210 |
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