ChemicalBook--->CAS DataBase List--->116539-60-7

116539-60-7

116539-60-7 Structure

116539-60-7 Structure
IdentificationBack Directory
[Name]

(R)-Duloxetine
[CAS]

116539-60-7
[Synonyms]

Ariclaim
(r)-duloxetine
(R)-Doluxitine
(-)-Duloxetine
R-DULOXETINE HCL
CYMBALTA; ARICLAIM
R-DULOXETINE Oxalate
(R)-Duloxetine USP/EP/BP
Duloxetine hydrochloride impurity A
Duloxetine hydrochloride impurity VII
Duloxetine hydrochloride impurity A -G
"(R)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan
N-methyl-3-(1-naphthalenyloxy)-3-thiophen-2-yl-1-propanamine
(r)-n-methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine
2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γR)
(R)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride
[EINECS(EC#)]

1312995-182-4
[Molecular Formula]

C18H19NOS.ClH
[MDL Number]

MFCD09750959
[MOL File]

116539-60-7.mol
[Molecular Weight]

333.881
Chemical PropertiesBack Directory
[Boiling point ]

466.2±40.0 °C(Predicted)
[density ]

1.158
[pka]

10.02±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

(R)-Duloxetine is a dual inhibitor of serotonin and norepinephrine reuptake, effective in the treatment of emotional and physical symptoms of depression
[Application]

Duloxetine (duloxetine) is a third-generation antidepressant launched in 2002, and its hydrochloride is clinically used under the trade name Cymbalta (Cymbalta).
[Definition]

ChEBI: (R)-duloxetine is a duloxetine. It is an enantiomer of a (S)-duloxetine.
[Synthesis]

(R)-Duloxetine was prepared from (S)-3-N,N-dimethylamino-1-(2-thienyl)-1-propanol 67.
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