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117739-40-9

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117739-40-9 Structure

117739-40-9 Structure
IdentificationBack Directory
[Name]

XX-650-23
[CAS]

117739-40-9
[Synonyms]

XX-650-23
2-Naphthalenecarboxamide, N-(4-cyanophenyl)-3-hydroxy-
[Molecular Formula]

C18H12N2O2
[MDL Number]

MFCD00142927
[MOL File]

117739-40-9.mol
[Molecular Weight]

288.3
Chemical PropertiesBack Directory
[Boiling point ]

454.0±30.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

8?+-.0.40(Predicted)
[color ]

Off-white to yellow
Hazard InformationBack Directory
[Uses]

XX-650-23 is a potent CREB inhibitor. XX-650-23inhibits CREB function through disruption of CBP-CREB interaction.?XX-650-23 can be used for AML research[1].
[References]

[1] B Mitton, et al. Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. Leukemia. 2016 Dec;30(12):2302-2311. DOI:10.1038/leu.2016.139
Spectrum DetailBack Directory
[Spectrum Detail]

XX-650-23(117739-40-9)1HNMR
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