ChemicalBook--->CAS DataBase List--->118488-18-9

118488-18-9

118488-18-9 Structure

118488-18-9 Structure
IdentificationMore
[Name]

Fmoc-D-Tyr(tBu)-OH
[CAS]

118488-18-9
[Synonyms]

9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-D-TYROSINE
FMOC-D-TYR(BUT)
FMOC-D-TYR(BUT)-OH
FMOC-D-TYROSINE(O-T-BUTYL)
FMOC-D-TYROSINE(TBU)-OH
FMOC-D-TYR(TBU)
FMOC-D-TYR(TBU)-OH
FMOC-O-T-BUTYL-D-TYROSINE
FMOC-O-TERT-BUTYL-D-TYROSINE
N-(9-fluorenylmethoxycarbonyl)-O-tert-butyl-D-tyrosine
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-T-BUTYL-D-TYROSINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-T-BUTYL-D-TYROSINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TERT-BUTYL-D-TYROSINE
N-ALPHA-FMOC-O-T-BUTYL-D-TYROSINE
N-ALPHA-FMOC-O-TERT-BUTYL-D-TYROSINE
FMOC-D-TYR(TBU)-OH 99%
NALPHA-9-Fluorenylmethoxycarbonyl-O-tert-butyl-D-tyrosine
N-α-Fmoc-O-tert-butyl-D-tyrosine
9-fluorenylmethyloxycarbonyl-D-tyrosine(tert-butyl)-OH
[Molecular Formula]

C28H29NO5
[MDL Number]

MFCD00065684
[Molecular Weight]

459.53
[MOL File]

118488-18-9.mol
Chemical PropertiesBack Directory
[Melting point ]

150.0 to 154.0 °C
[Boiling point ]

658.2±55.0 °C(Predicted)
[density ]

1.218±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

powder to crystal
[pka]

2.97±0.10(Predicted)
[color ]

White to Almost white
[Water Solubility ]

Soluble in 1 mmole in 2 ml dimethylformamide (Clearly soluble). Slightly soluble in water.
[BRN ]

6691868
[Major Application]

peptide synthesis
[InChIKey]

JAUKCFULLJFBFN-RUZDIDTESA-N
[SMILES]

C(O)(=O)[C@@H](CC1=CC=C(OC(C)(C)C)C=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
[CAS DataBase Reference]

118488-18-9(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H413-H317
[Precautionary statements ]

P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[F ]

10
[HS Code ]

29224999
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

Fmoc-D-Tyr(tBu)-OH is a precursor for the synthesis of thyroxine, dopa and adrenaline in medicine. It is directly involved in the synthesis of neurotransmitters such as dopamine, norepinephrine and epinephrine, and in the control of neurotransmitter levels, and is involved in the synthesis of hormones of thyroid, pituitary and other glands. In the feed industry, Fmoc-D-Tyr(tBu)-OH can be used as a feed additive in the feed of chicks. On the one hand, it minimizes the amount of phenylalanine converted to tyrosine to maintain the balance of amino acids in the growth of livestock and poultry. On the other hand, it can avoid chicks and piglets to lose weight due to insufficient tyrosine in the body and the destruction of thyroid and adrenal hormones.
[Chemical Properties]

White powder
[Uses]

N-Fmoc-O-tert-butyl-D-tyrosine is potentially useful for proteomics studies and solid phase peptide synthesis techniques.
[Definition]

Fmoc-D-Tyr(tBu)-OH (5mM) forms sphere-like assemblies at room temperature which may be converted to fibers-like structure on heating at 70 0C. In the case of Fmoc-D-Tyr(tBu)-OH, it formed a destructive aggregate at lower concentration instated of fibrils structure.
[benefits]

Taking Fmoc-D-Tyr(tBu)-OH can have an impact on the regulatory effects of mental, physical, metabolic, skin, growth rate, and psychology. It mainly has a good improvement effect on long-term fatigue, drowsiness, boredom, depression, frigidity, allergic reactions (allergies), headaches, anti-hunger, anti ultraviolet radiation, weight loss, blood pressure, Parkinson's disease, memory enhancement, attention deficit disorder, dementia, benzophenone medication, hangover, and mental stimulation in people
[reaction suitability]

reaction type: Fmoc solid-phase peptide synthesis
Spectrum DetailBack Directory
[Spectrum Detail]

Fmoc-D-Tyr(tBu)-OH(118488-18-9)1HNMR
Fmoc-D-Tyr(tBu)-OH(118488-18-9)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

118488-18-9(sigmaaldrich)
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