ChemicalBook--->CAS DataBase List--->1194044-20-6

1194044-20-6

1194044-20-6 Structure

1194044-20-6 Structure
IdentificationBack Directory
[Name]

LY2811376
[CAS]

1194044-20-6
[Synonyms]

CS-1893
LY2811376
LY2811376, >=98%
LY2811376 USP/EP/BP
LY 2811376;LY-2811376
(4S)-4-(2,4-difluoro-5-pyriMidin-5-ylphenyl)-4-Methyl-5,6-dihydro-1,3-thiazin-2-aMine
(S)-4-(2,4-difluoro-5-(pyriMidin-5-yl)phenyl)-4-Methyl-5,6-dihydro-4H-1,3-thiazin-2-aMine
(4S)-4-[2,4-Difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-4H-1,3-thiazin-2-amine
4H-1,3-Thiazin-2-amine, 4-[2,4-difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-, (4S)-
LY 2811376,(4S)-4-[2,4-Difluoro-5-(5-pyriMidinyl)phenyl]-5,6-dihydro-4-Methyl-4H-1,3-thiazin-2-aMine
N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride Tubastatin A HCl LY2811376
[Molecular Formula]

C15H14F2N4S
[MDL Number]

MFCD18074525
[MOL File]

1194044-20-6.mol
[Molecular Weight]

320.36
Chemical PropertiesBack Directory
[Boiling point ]

486.5±55.0 °C(Predicted)
[density ]

1.42
[pka]

5.60±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

LY 281137 is a compound capable of the decrease in β-amyloid peptide (Aβ) associated with the cleavage of amyloid precursor protein (APP) by β-secretase (BACE) and γ-secretase. This decrease is important as its hypothesized that the build up of (Aβ) in the brain is a primary cause of neurodegeneration and Alzheimer’s progression.
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