ChemicalBook--->CAS DataBase List--->119911-68-1

119911-68-1

119911-68-1 Structure

119911-68-1 Structure
IdentificationBack Directory
[Name]

ALPHA-CGRP (8-37) (HUMAN)
[CAS]

119911-68-1
[Synonyms]

FBHuman
α-cgrp 8-37
CGRP-I 8-37
Hcgrp (8-37)
Human CGRP(8-37)
alpha-Cgrp (8-37)
Human α-CGRP(8-37)
CGRP-I 8-37, HUMAN
CGRP (8-37), HUMAN
CGRP (HUMAN, 8-37)
Val(8)-Phe(37)-cgrp
A-CGRP (8-37) (HUMAN)
α-CGRP (8-37) (human)
α-CGRP 8-37, FBHuman
ALPHA-CGRP (HUMAN, 8-37)
ALPHA-CGRP (8-37) (HUMAN)
Erythropoietin Fragment 1-26
M.W. 3125.59 C139H230N44O38
VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2
calcitoningene-relatedpeptide(8-37
ALPHA-CGRP (8-37) (HUMAN) USP/EP/BP
CALCITONIN GENE RELATED PEPTIDE, HUMAN
Human calcitonin gene-related peptide(8-37)
8-Val-37-Phe-calcitonin gene-related peptide
CALCITONIN GENE RELATED PEPTIDE (8-37), HUMAN
CALCITONIN GENE RELATED PEPTIDE (HUMAN, 8-37)
CALCITONIN GENE-RELATED PEPTIDE-I 8-37, HUMAN
8-37-a-Calcitonin gene-related peptide(human)
8-37-α-Calcitonin gene-related peptide (human)
FBHuman Calcitonin Gene Related Peptide (8-37)
Alpha-CGRP (8-37) (human) trifluoroacetate salt
Calcitonin gene-related peptide, Val(8)-Phe(37)-
calcitonin gene related peptide*fragment 8-37 hum
CALCITONIN GENE RELATED PEPTIDE FRAGMENT 8-37 HUMAN
ALPHA-CALCITONIN GENE-RELATED PEPTIDE (8-37) (HUMAN)
Calcitonin gene-related peptide, valyl(8)-phenylalanine(37)-
Calcitonin gene related peptide fragment 8-37 human, ≥97% (HPLC)
α-CGRP 8-37, FBHuman Calcitonin Gene Related Peptide (8-37), human
α-CGRP (8-37) (human)|Calcitonin Gene Related Peptide (8-37), human
α-CGRP (8-37) (human),Calcitonin Gene-Related Peptide I (8-37) (human)
α-CGRP (8-37) (human),Calcitonin Gene-Related Peptide I (8-37) (human)
Calcitonin Gene-Related Peptide I (8-37) (huMan), CGRP-I (8-37) (huMan)
Calcitonin Gene Related Peptide Fragment 8-37 human >=97% (HPLC), powder
CalcitoninGeneRelatedPeptideFragMent8-37huMan,CalcitoninGeneRelatedPeptideFragMent
α-CGRP (8-37) (huMan) Calcitonin Gene-Related Peptide I (8-37) (huMan), CGRP-I (8-37) (huMan)
α-CGRP (8-37) (huMan) Calcitonin Gene-Related Peptide I (8-37) (huMan), CGRP-I (8-37) (huMan)
Ala-Pro-Pro-Arg-Leu-Ile-Cys-Asp-Ser-Arg-Val-Leu-Glu-Arg-Tyr-Leu-Leu-Glu-Ala-Lys-Glu-Ala-Glu-Asn-Ile-Thr
CALCITONIN GENE RELATED PEPTIDE FRAGMENT 8-37 HUMAN;Α-CGRP 8-37; FBHUMANCALCITONIN GENE RELATED PEPTIDE (8-37); HUMAN
VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2
H-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2
alpha-Calcitonin gene-related peptide (human reduced), 1-de-L-alanine-2-de-L-cysteine-3-de-L-aspartic acid-4-de-L-threonine-5-de-L-alanine-6-de-L-threonine-7-de-L-cysteine-
L-Val-L-Thr-L-His-L-Arg-L-Leu-L-Ala-Gly-L-Leu-L-Leu-L-Ser-L-Arg-L-Ser-Gly-Gly-L-Val-L-Val-L-Lys-L-Asn-L-Asn-L-Phe-L-Val-L-Pro-L-Thr-L-Asn-L-Val-Gly-L-Ser-L-Lys-L-Ala-L-Phe-NH2
ALA-CYS-ASN-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-ASP-PHE-LEU-SER-ARG-SER-GLY-GLY-VAL-GLY-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2: ACNTATCVTHRLADFLSRSGGVGKNNFVPTNVGSKAF-NH2DISULFIDE BRIDGE CYS2-CYS7
[EINECS(EC#)]

232-693-2
[Molecular Formula]

C139H230N44O38
[MDL Number]

MFCD00133153
[MOL File]

119911-68-1.mol
[Molecular Weight]

3125.59
Chemical PropertiesBack Directory
[density ]

1.46±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

powder
[Water Solubility ]

Soluble to 0.50 mg/ml in sterile water
[Sequence]

H-Val-Thr-His-Arg-Leu-Ala-Asp-Phe-Leu-Ser-Arg-Ser-Gly-Gly-Val-Gly-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Calcitonin Gene Related Peptide Fragment 8-37 human has been used in the administration of drugs. It has been used to test the hypothesis that calcitonin gene‐related peptide (CGRP) plays a role in the fetal cardiovascular and metabolic defense responses to acute hypoxaemia by affecting sympathetic outflow.
[General Description]

Calcitonin-related peptide α (CALCA) is a 37-amino-acid vasoactive neuropeptide. It is scattered in the central and peripheral nervous systems. The calcitonin/calcitonin gene-related peptide gene complex codes for a small family of peptides: calcitonin, katacalcin and CALCA. This vasodilator is potent than other vasodilators, such as adenosine, substance P or acetylcholine. CALCA gene is located on human chromosome 11p15.2-p15.1. Procalcitonin (PCT) is a calcitonin (CT) precursor.
[Biochem/physiol Actions]

Selective competitive antagonist at CGRP receptors, but not at calcitonin receptors.Calcitonin gene-related peptide (CALCA) serves as a proangiogenic growth factor in the development of human placenta. Mutations of CALCA gene is associated with Parkinson′s disease, ovarian cancer and essential hypertension. CALCA induce vascular endothelial cell proliferation, migration and capillary-like tube formation.
[storage]

Store at -20°C
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