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1206604-29-6

1206604-29-6 Structure

1206604-29-6 Structure
IdentificationBack Directory
[Name]

N-[(1,1-Dimethylethoxy)carbonyl]-L-methionyl-L-α-aspartylglycyl-L-cysteinyl-L-α-glutamyl-L-leucine
[CAS]

1206604-29-6
[Synonyms]

N-[(1,1-Dimethylethoxy)carbonyl]-L-methionyl-L-α-aspartylglycyl-L-cysteinyl-L-α-glutamyl-L-leucine
[Molecular Formula]

C30H50N6O13S2
[MOL File]

1206604-29-6.mol
[Molecular Weight]

766.88
Chemical PropertiesBack Directory
[Boiling point ]

1185.1±65.0 °C(Predicted)
[density ]

1.322±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[form ]

Solid
[pka]

3.34±0.10(Predicted)
[color ]

White to off-white
[Sequence]

{t-Boc}-Met-Asp-Gly-Cys-Glu-Leu
Hazard InformationBack Directory
[Uses]

Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma[1].
[References]

[1] Jenei V, et al. A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19473-8. DOI:10.1073/pnas.0909409106
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