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120667-15-4

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120667-15-4 Structure

120667-15-4 Structure
IdentificationBack Directory
[Name]

4-Phosphonophenylglycine
[CAS]

120667-15-4
[Synonyms]

(RS)-PPG
4-Phosphonophenylglycine
(RS)-PHOSPHONOPHENYLGLYCINE
(RS)-4-PHOSPHONOPHENYLGLYCINE
2-(4-phosphonoanilino)aceticaci
4-Phosphonophenylglycine USP/EP/BP
Benzeneacetic acid, α-amino-4-phosphono-
[Molecular Formula]

C8H10NO5P
[MDL Number]

MFCD02262122
[MOL File]

120667-15-4.mol
[Molecular Weight]

231.14
Chemical PropertiesBack Directory
[Boiling point ]

515.5±60.0 °C(Predicted)
[density ]

1.61±0.1 g/cm3(Predicted)
[storage temp. ]

Store at RT
[solubility ]

DMSO: soluble2mg/mL
[form ]

solid
[pka]

1.60±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

(RS)-PPG is a potent and selective group III mGluR agonist.
[Biological Activity]

A potent and selective group III metabotropic glutamate receptor agonist, with approximately 25-fold preference for hmGlu 8 ; anticonvulsant and neuroprotective in vivo . Also available as part of the Group III mGlu Receptor Tocriset™ .
[IC 50]

hmGluR8a: 0.2 μM (EC50); hmGluR6: 4.7 μM (EC50); hmGluR4a: 5.2 μM (EC50); hmGluR7b: 185 μM (EC50)
[storage]

Store at RT
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