| Identification | Back Directory | [Name]
Dalcotidine | [CAS]
120958-90-9 | [Synonyms]
KU 1257
Dalcotidine
Urea, N-ethyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]- | [Molecular Formula]
C18H29N3O2 | [MDL Number]
MFCD00880454 | [MOL File]
120958-90-9.mol | [Molecular Weight]
319.446 |
| Hazard Information | Back Directory | [Uses]
Dalcotidine (KU-1257) is an orally active and competitive histamine H2 receptor antagonist. Dalcotidine promotes the healing of chronic ulcers and inhibits gastric acid secretion[1][2]. | [Definition]
ChEBI: Dalcotidine is a member of piperidines. | [References]
[1] Sekiguchi H, et al. Healing-promoting action of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]urea with dual action on chronic gastric and duodenal ulcers induced by acetic acid in rats. Arzneimittelforschung. 1993;43(2):139-143. PMID:8096134
[2] Sekiguchi H, et al. Effects of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl] urea with potent gastric mucosal protective activity on acute gastric lesions and duodenal ulcers in rats. Arzneimittelforschung. 1993;43(2):134-138. PMID:8096133 |
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