| Identification | Back Directory | [Name]
2-(2-Propynyloxy)ethylamine | [CAS]
122116-12-5 | [Synonyms]
Alkyne-PEG1-NH2
Propargyl-PEG1-NH2
Propargyl-PEG1-amine
2-prop-2-ynoxyethanamine
2-(2-Propynyloxy)ethylamine
2-(2-Propyn-1-yloxy)ethanamine
2-(2-Propynyloxy)ethylamine >
Ethanamine, 2-(2-propyn-1-yloxy)-
2-(prop-2-yn-1-yloxy)Ethan-1-amine | [EINECS(EC#)]
808-208-0 | [Molecular Formula]
C5H9NO | [MDL Number]
MFCD16713446 | [MOL File]
122116-12-5.mol | [Molecular Weight]
99.13 |
| Chemical Properties | Back Directory | [Boiling point ]
153.4±15.0 °C(Predicted) | [density ]
0.945±0.06 g/cm3(Predicted) | [refractive index ]
1.4530 to 1.4570 | [form ]
clear liquid | [pka]
8.42±0.10(Predicted) | [color ]
Colorless to Light orange to Yellow |
| Hazard Information | Back Directory | [Uses]
Propargyl-PEG1-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG1-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
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