| Hazard Information | Back Directory | [Description]
L 722151 is a FXIIIa inhibitor. | [Uses]
L 722151 is a competitive inhibitor for factor XIIIa with Ki of 49 μM. L 722151 accelerates tissue plasminogen activator-catalyzed clot dissolution, and exhibits antithrombotic efficacy[1]. | [References]
[1] Al-Horani RA, et al., Factor XIIIa inhibitors as potential novel drugs for venous thromboembolism. Eur J Med Chem. 2020 Aug 15;200:112442. DOI:10.1016/j.ejmech.2020.112442 |
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