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1239-45-8

1239-45-8 Structure

1239-45-8 Structure
IdentificationMore
[Name]

Ethidium bromide
[CAS]

1239-45-8
[Synonyms]

1,7-DIAMINO-10-ETHYL-9-PHENYLPHENANTHRIDINIUM BROMIDE
2,7-DIAMINO-10-ETHYL-9-PHENYLPHENANTHRIDINIUM BROMIDE
2,7-DIAMINO-10-ETHYL-9-PHENYLPHENANTHRIDIUM BROMIDE
3,8-DIAMINO-5-ETHYL-6-PHENYLPHENANTHRIDINIUM BROMIDE
3,8-DIAMINO-5-ETHYL-6-PHENYLPHENANTHRIDIUM BROMIDE
3,8-DIAMINO-6-ETHYL-5-PHENYL-PHENANTHRIDIUM BROMIDE
5-ETHYL-3,8-DIAMINO-6-PHENYL-PHENANTHRIDINIUM BROMIDE
CA NUMBERING: 3,8-DIAMINO-5-ETHYL-6-PHENYL-PHENANTHRIDINIUM BROMIDE
ETBR
ETHIDIUM BROMIDE
HOMIDIUM BROMIDE
2,7-Diamino-9-phenyl-10-ethylphenanthridiniumbromide
2,7-Diamino-9-phenylphenanthridineethobromide
3,8-diamino-5-ethyl-6-phenyl-phenanthridiniubromide
Dromilac
Phenanthridinium,3,8-diamino-5-ethyl-6-phenyl-,bromide
Rd1572
Ethidium bromide(EB)
Ethidium bromide solution
3,8-diamino-1-ethyl-6-phenylphenantridinium bromide
[EINECS(EC#)]

214-984-6
[Molecular Formula]

C21H20BrN3
[MDL Number]

MFCD00011724
[Molecular Weight]

394.31
[MOL File]

1239-45-8.mol
Chemical PropertiesBack Directory
[Appearance]

Purple/maroon crystalline powder
[mp ]

260-262 °C (dec.)(lit.)
[Fp ]

>100°C
[storage temp. ]

2-8°C
[solubility ]

H2O: 10 mg/mL, opaque, strongly red
[form ]

powder
[Stability:]

Stable. Incompatible with strong oxidizing agents.
[Water Solubility ]

40 g/L (25 ºC)
[Merck ]

14,4731
[BRN ]

3642536
[CAS DataBase Reference]

1239-45-8(CAS DataBase Reference)
[EPA Substance Registry System]

1239-45-8(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

T,T+
[Risk Statements ]

R23:Toxic by inhalation.
R68:Possible risk of irreversible effects.
R36/37/38:Irritating to eyes, respiratory system and skin .
R26:Very Toxic by inhalation.
R21/22:Harmful in contact with skin and if swallowed .
R22:Harmful if swallowed.
[Safety Statements ]

S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S22:Do not breathe dust .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
[RIDADR ]

UN 2811 6.1/PG 1
[WGK Germany ]

3
[RTECS ]

SF7950000
[F ]

8-9
[HazardClass ]

6.1
[PackingGroup ]

I
[HS Code ]

29339990
[Safety Profile]

Poison by intraperitoneal and subcutaneous routes. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and Br-. See also BROMIDES.
[Hazardous Substances Data]

1239-45-8(Hazardous Substances Data)
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Homidium bromide(1239-45-8).msds
Questions And AnswerBack Directory
[description]

Ethidium Bromide (EtBr), commonly used in research laboratories as a stain for the visualization of nucleic acids in electrophoresis gels, is a toxic chemical and a potent mutagen. When used in nucleic acid staining, ethidium bromide fluoresces a red-orange to pink color under ultraviolet light and with increased fluorescence when bound to double-stranded DNA. While it is not specifically regulated as a hazardous waste, the mutagenic properties may present health hazards and disposal concerns if it is not managed properly in the laboratory.
[Uses]

Ethidium bromide (EtBr) is a fluorescent dye widely used in molecular biology research. Early usage was as a veterinary trypanocide. It is a mutagenic compound that intercalates double-stranded DNA and RNA. The fluorescence of EtBr increases 21-fold upon binding to double-stranded RNA, 25-fold on binding double-stranded DNA (although histones block binding of EtBr to DNA). Ethidium bromide has been used in multiple fluorimetric assays for nucleic acids. It has been shown to bind to single-stranded DNA (although not as strongly) and triple-stranded DNA. Because of the binding to DNA, EtBr is a powerful inhibitor of DNA polymerase.
Molecular Biology-grade Powder is suitable for use in gel electrophoresis and DNA isolation procedures.
Aqueous Solution (10 mg/mL) is suitable for use in gel electrophoresis and DNA isolation procedures.
Molecular Biology-grade Aqueous Solution (500 mg/mL) is suitable for use in gel electrophoresis.
[Health Hazards]

EtBr is a potent mutagen (may cause genetic damage), and moderately toxic after an acute exposure. EtBr can be absorbed through skin, so it is important to avoid any direct contact with the chemical. EtBr is an irritant to the skin, eyes, mouth, and upper respiratory tract. It should be stored away from strong oxidizing agents in a cool, dry place, and the container must be kept undamaged and tightly closed.
Spectrum DetailBack Directory
[Spectrum Detail]

Ethidium bromide(1239-45-8)MS
Ethidium bromide(1239-45-8)IR1
Ethidium bromide(1239-45-8)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Ethidium bromide, pure, 95%(1239-45-8)
[Alfa Aesar]

Ethidium bromide, 98% (dry wt.)(1239-45-8)
[Sigma Aldrich]

1239-45-8(sigmaaldrich)
[TCI AMERICA]

Ethidium Bromide,>90.0%(T)(1239-45-8)
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