| Identification | Back Directory | [Name]
Evogliptin hydrochloride | [CAS]
1246960-27-9 | [Synonyms]
DA1229
DA-1229
DA 1229
Evogliptin HCl
Evogliptin hydrochloride | [Molecular Formula]
C19H27ClF3N3O3 | [MOL File]
1246960-27-9.mol | [Molecular Weight]
437.89 |
| Hazard Information | Back Directory | [Description]
Evogliptin, also known as DA-1229, is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor). Evogliptin improves insulin resistance and delays the onset of diabetes. Evogliptin improves the insulin sensitivity in HF mice and delays the onset of diabetes in young db/db mice. DA-1229 monotherapy (5 mg for 12 weeks) improved HbA1c, fasting plasma glucose level, OGTT results and β-cell function. This drug was well tolerated in Korean subjects with type 2 diabetes mellitus. |
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Lynnchem
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