| Identification | Back Directory | [Name]
DiAzKs | [CAS]
1253643-88-7 | [Synonyms]
DiAzKs
H-L-Photo-lysine
Cross-Linking-Amino-Acid / DiAzK
N6-[[2-(3-Methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine | [Molecular Formula]
C11H20N4O4 | [MDL Number]
MFCD28133397 | [MOL File]
1253643-88-7.mol | [Molecular Weight]
272.3 |
| Chemical Properties | Back Directory | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble to 10 mM in water with gentle warming and to 100 mM in 1eq. HCl | [form ]
Solid | [pka]
2.53±0.24(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
H-L-Photo-lysine HCl is a diazirine-containing lysine amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (~360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907383. | [reaction suitability]
reaction type: solution phase peptide synthesis | [storage]
Store at -20°C |
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