| Identification | Back Directory | [Name]
taraxerol | [CAS]
127-22-0 | [Synonyms]
Alnulin
Taraxero
taraxeol
Skimmiol
Tiliadin
araxerol
β-Taraxerol
3β-Taraxerol
D-Friedoolean-14-en-3β-ol
(3β)-D-Friedoolean-14-en-3-ol
(3β13α)-13-Methyl-27-norolean-14-en-3-ol
27-Norolean-14-en-3-ol, 13-methyl-, (3β,13α)-
(3S,4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-octamethyl-1,2,3,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-icosahydropicen-3-ol | [Molecular Formula]
C30H50O | [MDL Number]
MFCD13186859 | [MOL File]
127-22-0.mol | [Molecular Weight]
426.72 |
| Chemical Properties | Back Directory | [Melting point ]
282-285° | [Boiling point ]
490.7±44.0 °C(Predicted) | [density ]
1.01±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
≥ 40 mg/mL in DMSO | [form ]
neat | [pka]
15.19±0.70(Predicted) | [color ]
White | [Water Solubility ]
insoluble in water | [Major Application]
food and beverages | [InChIKey]
GGGUGZHBAOMSFJ-GADYQYKKSA-N | [SMILES]
CC1(C)CC[C@]2(C)CC=C3[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@@]3(C)[C@]2([H])C1 | [LogP]
11.060 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Aster tataricus, Bambusa chinensis, and Taraxacum officinale. | [Uses]
β-Taraxerol has potential application against novel coronavirus SARS-?CoV-?2, in silico approach to assess the inhibitory potential. | [Definition]
ChEBI: A pentacyclic triterpenoid that is oleanan-3-ol lacking the methyl group at position 14, with an alpha-methyl substituent at position 13 and a double bond between positions 14 and 15. | [Synthesis]
The use of efficient extraction method of dandelion root in dandelion racemosanol extraction and separation, including the following steps: (1) reflux method of dandelion root to 30% ~ 95% ethanol solution extraction 1 ~ 3 times, each time 1 ~ 3 hours, th | [in vivo]
Taraxerol (5 and 10mg/kg; i.p.) attenuates carrageenan induced paw edema. The effect of taraxerol at the dose of 5mg/kg is found to be significant (p<0.05) only after 4h of carrageenan treatment[2]. | [target]
NO | PGE | TNF-α | IL Receptor | NF-kB | TGF-β/Smad | Akt |
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