ChemicalBook--->CAS DataBase List--->127481-29-2

127481-29-2

127481-29-2 Structure

127481-29-2 Structure
IdentificationBack Directory
[Name]

L 674573
[CAS]

127481-29-2
[Synonyms]

573
L674
L-674
L 674
L 674573
2-[[4-phenyl-1-[4-(2-quinolinylmethoxy)phenyl]butyl]thio]Acetic acid
Acetic acid, 2-[[4-phenyl-1-[4-(2-quinolinylmethoxy)phenyl]butyl]thio]-
[Molecular Formula]

C28H27NO3S
[MDL Number]

MFCD00889919
[MOL File]

127481-29-2.mol
[Molecular Weight]

457.58
Chemical PropertiesBack Directory
[Boiling point ]

656.0±55.0 °C(Predicted)
[density ]

1.235±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

3.73±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

L-674573 is a quinoline leukotriene synthesis inhibitor that selectively inhibits 5-lipoxygenase translocation[1].
[References]

[1] S Kargman, et al. Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors. J Biol Chem. 1991 Dec 15;266(35):23745-52. PMID:1748650
Spectrum DetailBack Directory
[Spectrum Detail]

L 674573(127481-29-2)1HNMR
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