| Identification | More | [Name]
SILVER LACTATE | [CAS]
128-00-7 | [Synonyms]
LACTIC ACID SILVER SALT
SILVER(I) LACTATE
SILVER LACTATE
SILVER LACTATE, FOR HISTOLOGY
Silver lactate solution, Ag 4-5% w/w (cont. Ag)
Lactic acid silver(I) salt | [Molecular Formula]
C3H5AgO3 | [MDL Number]
MFCD00043279 | [Molecular Weight]
196.94 | [MOL File]
128-00-7.mol |
| Chemical Properties | Back Directory | [Appearance]
grey powder | [Melting point ]
120-122 °C(lit.)
| [RTECS ]
UA2465550 | [storage temp. ]
Dark Room | [solubility ]
slightly soluble in H2O, ethanol | [form ]
Powder | [color ]
White to gray | [Water Solubility ]
soluble in ~15 parts H2O; slightly soluble alcohol [MER06] | [Sensitive ]
Light Sensitive | [Merck ]
14,8517 | [CAS DataBase Reference]
128-00-7(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
grey powder | [Purification Methods]
Recrystallise it from H2O by adding EtOH. The solid is collected, washed with EtOH, then Et2O, and dried at 80o to give the dihydrate. It is a white powder soluble in 15 parts of H2O but only slightly soluble in EtOH. Store it in the dark. [Engelhardt & Maddrell Justus Liebigs Ann Chem 63 89 1847, Karrer et al. Helv Chim Acta 2 251 1919, Beilstein 3 III 464.] |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
3-8-10 | [TSCA ]
No | [HazardClass ]
9 | [HS Code ]
28432900 |
| Questions And Answer | Back Directory | [Description]
Silver lactate is the silver salt of lactate. Silver lactate is a drug that can be used as antimicrobial agent in the external application. This is due to the effect of silver ion in killing bacteria via inhibiting respiratory pathway, destroying cell wall, impairing essential enzymes, obstructing metabolic activity and/or cause DNA stress. Its application in the treatment of thermal burn has been reported, thus being made into cream. Study has also found that it can decrease superoxide anion formation and chemotaxis in human polymorphonuclear leucocytes. Silver lactate staining can also be applied to the von Kossa reactions for calcium deposits to increases sensitivity and reduces background.
| [Reference]
- https://www.tandfonline.com/doi/pdf/10.1517/13543776.15.2.125
- Hoopes, J. E., et al. "Silver lactate burn cream." Surgery 70.1(1971): 29.
- Nalbandian, R. M., R. L. Henry, and H. S. Wilks. Journal of Biomedical Materials Research 6.6(1972): 583.
- Obel, N, et al. "Methyl mercury, mercuric chloride, and silver lactate decrease superoxide anion formation and chemotaxis in human polymorphonuclear leucocytes. " Human & Experimental Toxicology 12.5(1993): 361.
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