| Identification | More | [Name]
IODOANTIPYRINE | [CAS]
129-81-7 | [Synonyms]
1,2-DIHYDRO-4-IODO-1,5-DIMETHYL-2-PHENYL-3H-PYRAZOL-3-ONE 4-IODOANALGESINE 4-IODOANTIPYRINE 4-IODOPHENAZONE IODOANTIPYRINE LABOTEST-BB LT00454726 1,2-dihydro-4-iodo-1,5-dimethyl-2-phenyl-3h-pyrazol-3-on 4-iodo-antipyrin antipyrineiodide arthripur iodophenazone iodopyrine jodantipyrine jodopyrine 2,3-Dimethyl-4-iodo-1-phenyl-3-pyrazolin-5-one 4-iodo-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one 1,5-Dimethyl-4-iodo-2-phenyl-1,2-dihydro-pyrazol-3-one 2-Phenyl-1,5-dimethyl-4-iodo-1H-pyrazole-3(2H)-one | [EINECS(EC#)]
204-966-6 | [Molecular Formula]
C11H11IN2O | [MDL Number]
MFCD00040720 | [Molecular Weight]
314.12 | [MOL File]
129-81-7.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . | [RTECS ]
UQ9080000 | [Hazard Note ]
Irritant | [HS Code ]
2933399990 |
| Hazard Information | Back Directory | [Hazard]
Moderately toxic by ingestion. | [Uses]
Iodoantipyrine (4-Iodoantipyrine) is an iodinated Antipyrine (HY-B0171) with potential antiviral activity. Antipyrine (Phenazone) is an antipyretic and analgesic that also serves as a molecular probe of hepatic oxidative metabolites[1][2]. | [References]
[1] Evstropov A N, et al. Synthesis and antiviral activity of antipyrine derivatives[J]. Pharmaceutical Chemistry Journal, 1992, 26(5): 426-430. [2] Wilson L M E, et al. Iodination of antipyrine with [N–I–N]+ and carbonyl hypoiodite iodine (i) complexes[J]. New Journal of Chemistry, 2023, 47(6): 2978-2982. |
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