| Identification | Back Directory | [Name]
SeMilicoisoflavone B | [CAS]
129280-33-7 | [Synonyms]
PSX005
SeMilicoisoflavone B
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)- | [Molecular Formula]
C20H16O6 | [MDL Number]
MFCD28100710 | [MOL File]
129280-33-7.mol | [Molecular Weight]
352.34 |
| Chemical Properties | Back Directory | [Boiling point ]
615.5±55.0 °C(Predicted) | [density ]
1.443±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
6.43±0.20(Predicted) | [color ]
Light yellow to green yellow | [biological source]
plant | [Water Solubility ]
water: slightly soluble | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [InChI]
1S/C20H16O6/c1-20(2)4-3-10-5-11(6-15(23)19(10)26-20)13-9-25-16-8-12(21)7-14(22)17(16)18(13)24/h3-9,21-23H,1-2H3 | [InChIKey]
LWZACZCRAUQSLH-UHFFFAOYSA-N | [SMILES]
[o]1c2c([c](c(c1)c3cc4c(c(c3)O)OC(C=C4)(C)C)=O)c(cc(c2)O)O |
| Hazard Information | Back Directory | [Uses]
It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research. | [Definition]
ChEBI: A member of the class of 7-hydroxyisoflavones that is 2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one substituted by hydroxy groups at positions 5, 7 and 8'. It has been isolated from Glycyrrhiza uralensis. | [Biological Activity]
Semilicoisoflavone B:
- Suppresses proinflammatory cytokine productiondownregulates TLR4 expressionand diminishes reactive oxygen species generation in vitro.
- Inhibits the growth and division of cancer cells by triggering apoptosis and arresting the cell cycleoffering potential for effective tumor therapy.
- Restricts Caco-2 cell proliferationsuggesting potential for metabolic syndrome therapy.
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