| Identification | More | [Name]
2,2',4,4'-Tetrahydroxybenzophenone | [CAS]
131-55-5 | [Synonyms]
2,2,4,4 TETRAHYDROXY BENZOPHENONE
2,2',4,4'-TETRAHYDROXYBENZOPHENONE
BENZOPHENONE-2
BENZOPHENONE-2-(2,2',4,4'-TETRAHYDROXYBENZOPHENONE)
BIS-(2,4-DIHYDROXY-PHENYL)-METHANONE
DI(2,4-DIHYDROXYPHENYL)METHANONE
TIMTEC-BB SBB003178
2,2,4,4-Tetrahydroxybenzophenol
2,2’,4,4’-tetrahydroxy-benzophenon
2,2’,4,4’-tetrehydroxybenzophenone
2,4,2',4'-Tetrahydroxybenzophenone
2,4,2’,4’-tetrahydroxybenzophenone
Benzophenone, 2,2',4,4'-tetrahydroxy-
bis(2,4-dihydroxyphenyl)-methanon
Methanone, bis(2,4-dihydroxyphenyl)-
Uvinol D-50
Uvinul D-50
uvinuld-50
2,2',4,4'-Tetrahydroxybenzophenone(bp-2)
2,2',4,4'-Tetrahydroxybenzophe | [EINECS(EC#)]
205-028-9 | [Molecular Formula]
C13H10O5 | [MDL Number]
MFCD00002278 | [Molecular Weight]
246.22 | [MOL File]
131-55-5.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow to brown crystalline powder | [Melting point ]
198-200 °C(lit.)
| [Boiling point ]
349.21°C (rough estimate) | [density ]
1.216 | [refractive index ]
1.4825 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly, Sonicated), Methanol (Slightly) | [form ]
Solid | [pka]
6.98±0.35(Predicted) | [color ]
Needles from H2O | [Water Solubility ]
Slightly soluble in water. | [BRN ]
1914746 | [Stability:]
Hygroscopic | [Contact allergens]
BZP-2 is widely used in perfumes to prevent their degradation
due to light. It can cause allergic contact
dermatitis. | [InChIKey]
WXNRYSGJLQFHBR-UHFFFAOYSA-N | [LogP]
3.091 (est) | [Uses]
benzophenone-2 is a uV-absorber that helps protect against product degradation because of uV-light exposure. It can also mask odor associated with a formulation’s composition. | [CAS DataBase Reference]
131-55-5(CAS DataBase Reference) | [NIST Chemistry Reference]
2,2',4,4'-Tetrahydroxybenzophenone(131-55-5) | [EPA Substance Registry System]
131-55-5(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
yellow to brown crystalline powder | [Uses]
Sunscreen | [Preparation]
Obtained (small amount) by melting a fluorescin chloride/sodium hydroxide mixture in the presence of a very few water at 230–240° for 2–3 h. | [Safety Profile]
Moderately toxic by ingestion. Aneye irritant. Mutation data reported. When heated todecomposition it emits toxic fumes of NOx. |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
DJ1892000
| [TSCA ]
Yes | [HS Code ]
29145090 | [Hazardous Substances Data]
131-55-5(Hazardous Substances Data) | [Toxicity]
LD50 oral in rat: 1220mg/kg |
| Questions And Answer | Back Directory | [Application]
2,2',4,4'-Tetrahydroxybenzophenone (BZP-2) is water-soluble and light-yellow powder (figure 1). BZP-2 is widely used in perfumes to prevent their degradation due to light. BZP-2 is a UV-absorber that helps protect against product degradation because of UV-light exposure and it is widely used in sunscreens and in cosmetics (figure 2), such as: anti-aging” creams and hair sprays and shampoos, paints and plastics. It can also mask odor associated with a formulation’s composition. In addition, the hypolipemiant drug fenofibrate is also a substituted benzophenone. | [Potential Exposure & Risk]
Although 2,2',4,4'-Tetrahydroxybenzophenone is used as a UV-blocker in cosmetics, plastics and automotive car products, its safety issue still should be noted. Such as workers that use BZP-2 may breathe in dust or have direct skin contact and the general population may be exposed by dermal contact with products containing this compound.
Skin allergic reaction has been reported in some people using sunscreens or cosmetics containing this compound. 2,2',4,4'-Tetrahydroxybenzophenone(BZP-2) is a member of a group of chemicals known as endocrine disruptors, which may alter the function and/or development of the reproductive system. Limited evidence indicates that exposure to benzophenone UV-absorbing chemicals, including BZP-2, is associated with an altered ratio of males to females at birth (increased females). |
| Spectrum Detail | Back Directory | [Spectrum Detail]
2,2',4,4'-Tetrahydroxybenzophenone(131-55-5)MS
2,2',4,4'-Tetrahydroxybenzophenone(131-55-5)1HNMR
2,2',4,4'-Tetrahydroxybenzophenone(131-55-5)13CNMR
2,2',4,4'-Tetrahydroxybenzophenone(131-55-5)IR1
2,2',4,4'-Tetrahydroxybenzophenone(131-55-5)IR2
2,2',4,4'-Tetrahydroxybenzophenone(131-55-5)Raman
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